Abstract
The effectiveness of treatments for the mother exposed to adverse events in pregnancy is not always interpreted in the light of possible effects on the child. The follow-up of infants is an important component of obstetric and perinatal audit not only in randomised clinical trials but as part of routine health care. The results of the 18 month's follow-up of children born from women recruited in the Italian Study of Aspirin in Pregnancy and in the Italian Trial on Nifedipine in Pregnancy are discussed. No significant differences emerged between treatment and no-treatment groups with respect to indicators of development and health status. Malformations, diseases, and other health problems showed no specific patterns and were much the same in the groups. Our findings suggest that the use of low-dose aspirin and calcium channel blocker nifedipine in pregnancy is safe with respect to the risks of malformation and of major impairment in development at 18 months of age.
| Original language | Italian |
|---|---|
| Pages (from-to) | 243-248 |
| Number of pages | 6 |
| Journal | Pediatria Medica e Chirurgica |
| Volume | 21 |
| Issue number | 6 |
| Publication status | Published - 1999 |
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ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Il follow-up dei bambini nei trial clinici ostetrici : Esperienze di ricerca in Italia. / Bortolus, R.; Parazzini, F.; Zanardo, V.
In: Pediatria Medica e Chirurgica, Vol. 21, No. 6, 1999, p. 243-248.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Il follow-up dei bambini nei trial clinici ostetrici
T2 - Esperienze di ricerca in Italia
AU - Bortolus, R.
AU - Parazzini, F.
AU - Zanardo, V.
PY - 1999
Y1 - 1999
N2 - The effectiveness of treatments for the mother exposed to adverse events in pregnancy is not always interpreted in the light of possible effects on the child. The follow-up of infants is an important component of obstetric and perinatal audit not only in randomised clinical trials but as part of routine health care. The results of the 18 month's follow-up of children born from women recruited in the Italian Study of Aspirin in Pregnancy and in the Italian Trial on Nifedipine in Pregnancy are discussed. No significant differences emerged between treatment and no-treatment groups with respect to indicators of development and health status. Malformations, diseases, and other health problems showed no specific patterns and were much the same in the groups. Our findings suggest that the use of low-dose aspirin and calcium channel blocker nifedipine in pregnancy is safe with respect to the risks of malformation and of major impairment in development at 18 months of age.
AB - The effectiveness of treatments for the mother exposed to adverse events in pregnancy is not always interpreted in the light of possible effects on the child. The follow-up of infants is an important component of obstetric and perinatal audit not only in randomised clinical trials but as part of routine health care. The results of the 18 month's follow-up of children born from women recruited in the Italian Study of Aspirin in Pregnancy and in the Italian Trial on Nifedipine in Pregnancy are discussed. No significant differences emerged between treatment and no-treatment groups with respect to indicators of development and health status. Malformations, diseases, and other health problems showed no specific patterns and were much the same in the groups. Our findings suggest that the use of low-dose aspirin and calcium channel blocker nifedipine in pregnancy is safe with respect to the risks of malformation and of major impairment in development at 18 months of age.
KW - Hypertension
KW - Pediatric follow-up
KW - Pregnancy
UR - http://www.scopus.com/inward/record.url?scp=0033281516&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033281516&partnerID=8YFLogxK
M3 - Articolo
C2 - 11293143
AN - SCOPUS:0033281516
VL - 21
SP - 243
EP - 248
JO - Pediatria Medica e Chirurgica
JF - Pediatria Medica e Chirurgica
SN - 0391-5387
IS - 6
ER -