Follow-up of Oral Leukoplakia After Carbon Dioxide Laser Surgery

Fausto Chiesa, Nicoletta Tradati, Luigi Sala, Luigi Costa, Stefano Podrecca, Patrizia Boracchi, Gaetano Bandieramonte, Maurizio Mauri, Roberto Molinari

Research output: Contribution to journalArticlepeer-review


• We evaluate the 3-year result of 145 oral leukoplakias operated on by outpatient carbon dioxide laser surgery at the Istituto Nazionale Tumori, Milan, Italy. The surgical technique that was used consisted of excision in 140 patients and vaporization in 5 patients. Cancer was found in 14 out of 140 patients who underwent excision (10%). In the analysis of the disease-free survival rate and of the unfavorable pattern of events, only 131 patients with benign postoperative histologic diagnosis were considered. Fifty-eight patients developed unfavorable events. The probabilities of remaining free of disease or of developing local relapses or new lesions at 3-year survival was 0.57, 0.27, and 0.19, respectively. Two patients had oral carcinomas after the operation. Forty patients modified their alcohol or tobacco habits or their teeth and/or prosthesis. Moreover, only two patients modified these factors before the unfavorable events occurred. (Arch Otolaryngol Head Neck Surg. 1990;116:177-180).

Original languageEnglish
Pages (from-to)177-180
Number of pages4
JournalArchives of Otolaryngology - Head and Neck Surgery
Issue number2
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Surgery


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