Follow-up of patients with early breast cancer: Is it time to rewrite the story?

Fabio Puglisi, Caterina Fontanella, Gianmauro Numico, Valentina Sini, Laura Evangelista, Francesco Monetti, Stefania Gori, Lucia Del Mastro

Research output: Contribution to journalArticle

Abstract

The guidelines for follow-up in breast cancer survivors support only performance of periodic physical examination and annual mammography. However, medical oncologists and primary care physicians routinely recommend both blood tests and non-mammographic imaging tests in asymptomatic patients, leading to an increased anxiety related to false-positive results and higher medical expenses. Recently, advanced imaging technologies have improved sensitivity/specificity to detect metastatic lesions before symptoms arise. Considering the progress made in the treatment of metastatic disease and the rapid evolution of targeted therapy, that requires customization of the strategy according to molecular characteristics of the disease, patients could derive real benefit to early detection of disease recurrence. This hypothesis must be tested in a prospective clinical trial.

Original languageEnglish
Pages (from-to)130-141
Number of pages12
JournalCritical Reviews in Oncology/Hematology
Volume91
Issue number2
DOIs
Publication statusPublished - 2014

Keywords

  • Early breast cancer
  • Follow-up
  • Surveillance
  • Survivorship care

ASJC Scopus subject areas

  • Oncology
  • Hematology
  • Geriatrics and Gerontology
  • Medicine(all)

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