Food restriction in female Wistar rats, IV. Morphometric parameters of cerebellar synapses

C. Pieri, F. Marcheselli, M. Falasca, F. Moroni, R. Recchioni

Research output: Contribution to journalArticlepeer-review

Abstract

The effect of food restriction on morphometric parameters of cerebellar synapses has been evaluated. A decrease in the number and surface density of synapses has been observed comparing 6 and 27-28 month old rats. Food restriction prevented the loss of the number and attenuated the reduction of the surface density of synaptic contacts occurring during aging. Present data support the idea that food restriction delays the appearance of age-related modifications of synaptic structures and may explain the improvement of motoric coordination and performance found in dietary restricted old animals.

Original languageEnglish
Pages (from-to)161-165
Number of pages5
JournalArchives of Gerontology and Geriatrics
Volume13
Issue number2
DOIs
Publication statusPublished - 1991

Keywords

  • Cerebellum
  • Morphometry
  • Synapses
  • Undernutrition

ASJC Scopus subject areas

  • Ageing
  • Medicine(all)

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