TY - JOUR
T1 - Four-week urticaria activity score-7 as a useful patient-reported outcome to assess chronic spontaneous urticaria
T2 - A multicentre study evaluation of adherence and patients’ perspective
AU - Patruno, Cataldo
AU - Napolitano, Maddalena
AU - Ferrucci, Silvia
AU - Brambilla, Lucia
AU - Hansel, Katharina
AU - Corazza, Monica
AU - Schena, Donatella
AU - Foti, Caterina
AU - Romita, Paolo
AU - Gallo, Rosella
AU - Stingeni, Luca
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Chronic spontaneous urticaria (CSU) is a condition characterized by the recurrence of itchy wheals without any specific trigger for longer than 6 weeks (1). In CSU the wheals fluctuate throughout the day. Therefore, measurement of the activity of the disease and of the effectiveness of treatments is by means of patient-reported outcome (PRO) instruments, such as the Urticaria Activity Score (UAS) (2). The UAS is a quantitative daily diary that includes a once-a-day (3) or twice-a-day (4) self-evaluation score. It is used for both clinical practice and trials to assess disease activity and treatment efficacy (1). Due to the chronicity and remarkable instability of CSU, daily UAS scores are summed over one week to create the UAS7 (3). However, there is a lack of information on adherence to the instrument and the precision with which it is completed. The aim of this study was to evaluate adherence to the once-a-day UAS7 in real life, through an observational, descriptive, multicentre study on consecutive patients with CSU aged ≥18 years.
AB - Chronic spontaneous urticaria (CSU) is a condition characterized by the recurrence of itchy wheals without any specific trigger for longer than 6 weeks (1). In CSU the wheals fluctuate throughout the day. Therefore, measurement of the activity of the disease and of the effectiveness of treatments is by means of patient-reported outcome (PRO) instruments, such as the Urticaria Activity Score (UAS) (2). The UAS is a quantitative daily diary that includes a once-a-day (3) or twice-a-day (4) self-evaluation score. It is used for both clinical practice and trials to assess disease activity and treatment efficacy (1). Due to the chronicity and remarkable instability of CSU, daily UAS scores are summed over one week to create the UAS7 (3). However, there is a lack of information on adherence to the instrument and the precision with which it is completed. The aim of this study was to evaluate adherence to the once-a-day UAS7 in real life, through an observational, descriptive, multicentre study on consecutive patients with CSU aged ≥18 years.
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U2 - 10.2340/00015555-3231
DO - 10.2340/00015555-3231
M3 - Article
C2 - 31141154
AN - SCOPUS:85071709500
VL - 99
SP - 903
EP - 904
JO - Acta Dermato-Venereologica
JF - Acta Dermato-Venereologica
SN - 0001-5555
IS - 10
ER -