Fournier's gangrene: A clinical presentation of necrotizing fasciitis after bone marrow transplantation

G. Martinelli, E. P. Alessandrino, P. Bernasconi, D. Caldera, A. Colombo, L. Malcovati, M. R. Gaviglio, G. P. Vignoli, G. Borroni, C. Bernasconi

Research output: Contribution to journalArticle

Abstract

Three patients with ANLL developed Fournier's gangrene as an early complication after allo-BMT (two cases) and auto-BMT (one case); two patients were in first CR, the third had resistant disease. Patients developed fever, perineal pain, swelling and blistering of the genital area. Pseudomonas aeruginosa was isolated from the lesions and patients received systemic antibiotic therapy, surgical debridement and medication with potassium permanganate solution. Two patients made a complete recovery although one died of sepsis. The third had progressive involvement of the abdominal wall and later died of leukemia. Early diagnosis of this disorder and prompt initiation of appropriate therapy can prevent progression of this acute necrotizing infection.

Original languageEnglish
Pages (from-to)1023-1026
Number of pages4
JournalBone Marrow Transplantation
Volume22
Issue number10
Publication statusPublished - 1998

Fingerprint

Fournier Gangrene
Necrotizing Fasciitis
Bone Marrow Transplantation
Potassium Permanganate
Abdominal Wall
Debridement
Acute Myeloid Leukemia
Pseudomonas aeruginosa
Early Diagnosis
Sepsis
Leukemia
Fever
Anti-Bacterial Agents
Pain
Therapeutics
Infection

Keywords

  • Bone marrow transplantation
  • Fournier's gangrene
  • Necrotizing fasciitis

ASJC Scopus subject areas

  • Hematology
  • Transplantation

Cite this

Fournier's gangrene : A clinical presentation of necrotizing fasciitis after bone marrow transplantation. / Martinelli, G.; Alessandrino, E. P.; Bernasconi, P.; Caldera, D.; Colombo, A.; Malcovati, L.; Gaviglio, M. R.; Vignoli, G. P.; Borroni, G.; Bernasconi, C.

In: Bone Marrow Transplantation, Vol. 22, No. 10, 1998, p. 1023-1026.

Research output: Contribution to journalArticle

Martinelli, G, Alessandrino, EP, Bernasconi, P, Caldera, D, Colombo, A, Malcovati, L, Gaviglio, MR, Vignoli, GP, Borroni, G & Bernasconi, C 1998, 'Fournier's gangrene: A clinical presentation of necrotizing fasciitis after bone marrow transplantation', Bone Marrow Transplantation, vol. 22, no. 10, pp. 1023-1026.
Martinelli, G. ; Alessandrino, E. P. ; Bernasconi, P. ; Caldera, D. ; Colombo, A. ; Malcovati, L. ; Gaviglio, M. R. ; Vignoli, G. P. ; Borroni, G. ; Bernasconi, C. / Fournier's gangrene : A clinical presentation of necrotizing fasciitis after bone marrow transplantation. In: Bone Marrow Transplantation. 1998 ; Vol. 22, No. 10. pp. 1023-1026.
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