Free laminin in the extracellular matrix of B-cell non Hodgkin's lymphomas

D. Ribatti, A. Vacca, B. Nico, F. Quondamatteo, R. Herken, L. Roncali

Research output: Contribution to journalArticlepeer-review

Abstract

The authors show that in the perivascular stroma of B-cell non-Hodgkin's lymphomas (B-NHL) is present a granular, speckled pattern of expression of laminin, similar to the 'free-laminin' firstly described by Lugassy et al. (1997) in human melanoma. The role of this form of laminin may be to promote the migration of tumor cells, which express a variety of binding-laminin surface proteins, whose expression is significantly increased in several human cancer models.

Original languageEnglish
Pages (from-to)459-461
Number of pages3
JournalJournal of Submicroscopic Cytology and Pathology
Volume30
Issue number3
Publication statusPublished - Jul 1998

Keywords

  • Angiogenesis
  • B-cell non Hodgkin's lymphomas
  • Laminin
  • Tumor progression

ASJC Scopus subject areas

  • Cell Biology
  • Histology
  • Pathology and Forensic Medicine

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