Abstract
Frequency and correlates of severe hypoglycaemia have been retrospectively analysed in a cohort of diabetic children and adolescents with median (range) age 14.5 (3.2-25.5) years followed from the onset of the disease by the same diabetic clinic. During the years 1992-1994, 53 of the 187 patients reported 74 hypoglycaemic episodes: the average frequency of hypoglycaemia during the 3 years surveyed was 14.9 episodes 100 patients per year. Frequency of hypoglycaemia decreased significantly with age (χ2 = 24.1; P <0.0001) and was independent of duration of diabetes. Glycosylated haemoglobin and insulin dose were similar in patients with and without hypoglycaemia, matched for age and duration of diabetes. One out of two hypoglycaemic episodes occurred during sleep and no explanation was available for 50% of episodes. Conclusion: In this study severe hypoglycaemia was more frequent in young children than in adolescents and was independent of metabolic control and insulin dose.
| Original language | English |
|---|---|
| Pages (from-to) | 589-591 |
| Number of pages | 3 |
| Journal | European Journal of Pediatrics |
| Volume | 156 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 1997 |
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Keywords
- Glycosylated haemoglobin
- Insulin dependent diabetes mellitus
- Severe hypoglycaemia
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Frequency and correlates of severe hypoglycaemia in children and adolescents with diabetes mellitus. / Bognetti, E.; Brunelli, A.; Meschi, F.; Viscardi, M.; Bonfanti, R.; Chiumello, G.
In: European Journal of Pediatrics, Vol. 156, No. 8, 1997, p. 589-591.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Frequency and correlates of severe hypoglycaemia in children and adolescents with diabetes mellitus
AU - Bognetti, E.
AU - Brunelli, A.
AU - Meschi, F.
AU - Viscardi, M.
AU - Bonfanti, R.
AU - Chiumello, G.
PY - 1997
Y1 - 1997
N2 - Frequency and correlates of severe hypoglycaemia have been retrospectively analysed in a cohort of diabetic children and adolescents with median (range) age 14.5 (3.2-25.5) years followed from the onset of the disease by the same diabetic clinic. During the years 1992-1994, 53 of the 187 patients reported 74 hypoglycaemic episodes: the average frequency of hypoglycaemia during the 3 years surveyed was 14.9 episodes 100 patients per year. Frequency of hypoglycaemia decreased significantly with age (χ2 = 24.1; P <0.0001) and was independent of duration of diabetes. Glycosylated haemoglobin and insulin dose were similar in patients with and without hypoglycaemia, matched for age and duration of diabetes. One out of two hypoglycaemic episodes occurred during sleep and no explanation was available for 50% of episodes. Conclusion: In this study severe hypoglycaemia was more frequent in young children than in adolescents and was independent of metabolic control and insulin dose.
AB - Frequency and correlates of severe hypoglycaemia have been retrospectively analysed in a cohort of diabetic children and adolescents with median (range) age 14.5 (3.2-25.5) years followed from the onset of the disease by the same diabetic clinic. During the years 1992-1994, 53 of the 187 patients reported 74 hypoglycaemic episodes: the average frequency of hypoglycaemia during the 3 years surveyed was 14.9 episodes 100 patients per year. Frequency of hypoglycaemia decreased significantly with age (χ2 = 24.1; P <0.0001) and was independent of duration of diabetes. Glycosylated haemoglobin and insulin dose were similar in patients with and without hypoglycaemia, matched for age and duration of diabetes. One out of two hypoglycaemic episodes occurred during sleep and no explanation was available for 50% of episodes. Conclusion: In this study severe hypoglycaemia was more frequent in young children than in adolescents and was independent of metabolic control and insulin dose.
KW - Glycosylated haemoglobin
KW - Insulin dependent diabetes mellitus
KW - Severe hypoglycaemia
UR - http://www.scopus.com/inward/record.url?scp=0030744662&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030744662&partnerID=8YFLogxK
U2 - 10.1007/s004310050670
DO - 10.1007/s004310050670
M3 - Article
C2 - 9266186
AN - SCOPUS:0030744662
VL - 156
SP - 589
EP - 591
JO - European Journal of Pediatrics
JF - European Journal of Pediatrics
SN - 0340-6199
IS - 8
ER -