Abstract
The rates of non-albicans species and susceptibility to the main antimycotic drugs were evaluated in a series of 472 cultures of vulvar or vaginal specimens positive for Candida species. Torulopsis glabrata was associated more frequently than C. albicans with recurrent vulvovaginal candidiasis (18/40 vs. 72/379; p = 0.003, X2 test). As evaluated by the results of susceptibility testing, C. albicans isolates were uniformly sensitive to the antifungals tested, whereas 7.5% (3/40) of T. glabrata strains were resistant to imidazole derivatives. All these patients had a history of repeated antimycotic treatments. Previous antimycotic therapies in susceptible individuals could cause a selection of non- albicans species, especially T. glabrata, which is occasionally resistant to the commonly used antimycoticdrugs.
Original language | English |
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Pages (from-to) | 130-133 |
Number of pages | 4 |
Journal | Gynecologic and Obstetric Investigation |
Volume | 38 |
Issue number | 2 |
DOIs | |
Publication status | Published - 1994 |
Keywords
- Candida albicans
- Dresistance
- Torulopsis glabrata
- Vulvovaginitis drug
ASJC Scopus subject areas
- Obstetrics and Gynaecology
- Reproductive Medicine