Frequency of Coronary Artery Bypass Grafting Following Implantation of a Paclitaxel-Eluting or a Bare-Metal Stent Into a Single Coronary Artery

Jack L. Martin, Stephen G. Ellis, Antonio Colombo, Eberhard Grube, Tom Maloney, Mark I. Friedman, Donald S. Baim, Keith Dawkins, Ron Caputo, Gregg W. Stone

Research output: Contribution to journalArticle

Abstract

Limited data are available on the relative effect of drug-eluting versus bare-metal stents on the requirement for subsequent coronary artery bypass grafting (CABG). The aim of this study was to evaluate the incidence and predictors of CABG after bare-metal and paclitaxel-eluting coronary stent implantation. A patient-level, pooled analysis was conducted of 2,736 patients from 3 double-blind, randomized trials comparing the slow-release paclitaxel-eluting Taxus stent with an otherwise identical bare-metal stent control in single de novo coronary lesions, with 5-year follow-up. The rate of target lesion revascularization by CABG (TLR-CABG) was reduced from 4.1% in patients with bare-metal stents to 1.4% in those with Taxus stents (p

Original languageEnglish
Pages (from-to)11-16
Number of pages6
JournalThe American Journal of Cardiology
Volume103
Issue number1
DOIs
Publication statusPublished - Jan 1 2009

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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    Martin, J. L., Ellis, S. G., Colombo, A., Grube, E., Maloney, T., Friedman, M. I., Baim, D. S., Dawkins, K., Caputo, R., & Stone, G. W. (2009). Frequency of Coronary Artery Bypass Grafting Following Implantation of a Paclitaxel-Eluting or a Bare-Metal Stent Into a Single Coronary Artery. The American Journal of Cardiology, 103(1), 11-16. https://doi.org/10.1016/j.amjcard.2008.08.025