Frequency of Coronary Artery Bypass Grafting Following Implantation of a Paclitaxel-Eluting or a Bare-Metal Stent Into a Single Coronary Artery

Jack L. Martin, Stephen G. Ellis, Antonio Colombo, Eberhard Grube, Tom Maloney, Mark I. Friedman, Donald S. Baim, Keith Dawkins, Ron Caputo, Gregg W. Stone

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Limited data are available on the relative effect of drug-eluting versus bare-metal stents on the requirement for subsequent coronary artery bypass grafting (CABG). The aim of this study was to evaluate the incidence and predictors of CABG after bare-metal and paclitaxel-eluting coronary stent implantation. A patient-level, pooled analysis was conducted of 2,736 patients from 3 double-blind, randomized trials comparing the slow-release paclitaxel-eluting Taxus stent with an otherwise identical bare-metal stent control in single de novo coronary lesions, with 5-year follow-up. The rate of target lesion revascularization by CABG (TLR-CABG) was reduced from 4.1% in patients with bare-metal stents to 1.4% in those with Taxus stents (p

Original languageEnglish
Pages (from-to)11-16
Number of pages6
JournalThe American Journal of Cardiology
Volume103
Issue number1
DOIs
Publication statusPublished - Jan 1 2009

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Paclitaxel
Coronary Artery Bypass
Stents
Coronary Vessels
Metals
Taxus
Incidence
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Frequency of Coronary Artery Bypass Grafting Following Implantation of a Paclitaxel-Eluting or a Bare-Metal Stent Into a Single Coronary Artery. / Martin, Jack L.; Ellis, Stephen G.; Colombo, Antonio; Grube, Eberhard; Maloney, Tom; Friedman, Mark I.; Baim, Donald S.; Dawkins, Keith; Caputo, Ron; Stone, Gregg W.

In: The American Journal of Cardiology, Vol. 103, No. 1, 01.01.2009, p. 11-16.

Research output: Contribution to journalArticle

Martin, JL, Ellis, SG, Colombo, A, Grube, E, Maloney, T, Friedman, MI, Baim, DS, Dawkins, K, Caputo, R & Stone, GW 2009, 'Frequency of Coronary Artery Bypass Grafting Following Implantation of a Paclitaxel-Eluting or a Bare-Metal Stent Into a Single Coronary Artery', The American Journal of Cardiology, vol. 103, no. 1, pp. 11-16. https://doi.org/10.1016/j.amjcard.2008.08.025
Martin, Jack L. ; Ellis, Stephen G. ; Colombo, Antonio ; Grube, Eberhard ; Maloney, Tom ; Friedman, Mark I. ; Baim, Donald S. ; Dawkins, Keith ; Caputo, Ron ; Stone, Gregg W. / Frequency of Coronary Artery Bypass Grafting Following Implantation of a Paclitaxel-Eluting or a Bare-Metal Stent Into a Single Coronary Artery. In: The American Journal of Cardiology. 2009 ; Vol. 103, No. 1. pp. 11-16.
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