Fresh-socket implants in periapical infected sites in humans

Roberto Crespi, Paolo Capparè, Enrico Gherlone

Research output: Contribution to journalArticlepeer-review


Background: The aim of the present study is to compare the outcome of the immediate placement of implants when used in the replacement of teeth with and without chronic periapical lesions. Methods: Thirty patients requiring a single-tooth extraction of a monoradicular or premolar tooth were selected. The control group (CG) included 15 patients without periapical lesions but with root caries and root fractures. The test group (TG) included 15 patients with periapical lesions, periapical radiolucencies, and no signs of pain, fistulas, or suppuration. Thirty teeth were extracted, and implants were immediately positioned in fresh sockets and loaded after 3 months in both groups. Clinical parameters (probing depth [PD], modified plaque index, modified bleeding index [mBI], marginal gingiva level [MGL], and keratinized mucosa [KM]) and marginal bone levels were evaluated at baseline and 12 and 24 months after implant placement. Comparisons between CG and TG values over time were performed by the Student two-tailed t test. Results: At the 24-month follow-up, a survival rate of 100% was reported for all implants. The mean bone loss was 0.82 ± 0.52 mm for the CG and 0.86 ± 0.54 for the TG. Plaque accumulation was 0.74 ± 0.29 for the CG and 0.69 ± 0.29 for the TG. The mBI was 0.77 ± 0.33 for the CG and 0.72 ± 0.36 for the TG. The soft tissue profile MGL and KM remained stable for up to 24 months for the CG and TG. The mean PD was 2.05 ± 0.66mmfor the CG and 1.99 ± 0.57mmfor the TG. Differences that were not statistically significant were reported between the CG and TG over time and between time points. Conclusion: At the 24-month follow-up, endosseous implants placed immediately in extraction sites affected by periapical infection rendered an equally favorable soft and hard tissue integration of the implants, revealing a predictable outcome. J Periodontol 2010;81:378-383.

Original languageEnglish
Pages (from-to)378-383
Number of pages6
JournalJournal of Periodontology
Issue number3
Publication statusPublished - Mar 2010


  • Dental implants
  • Infection
  • Periodontitis
  • Tooth socket

ASJC Scopus subject areas

  • Periodontics


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