From castration-induced apoptosis of prostatic epithelium to the use of apoptotic genes in the treatment of prostate cancer

Y. Zhang, Bicheng Nan, Jiang Yu, Tithi Snabboon, Francesca Andriani, Marco Marcelli

Research output: Contribution to journalArticlepeer-review

Abstract

Current knowledge of the mechanisms regulating androgen-ablation-induced apoptosis is reviewed, and our efforts to develop a system in which genes of the apoptotic pathway are used to induce therapeutic apoptosis in experimental models of prostate cancer are described.

Original languageEnglish
Pages (from-to)191-203
Number of pages13
JournalAnnals of the New York Academy of Sciences
Volume963
Publication statusPublished - 2002

Keywords

  • Apoptosis
  • Castration
  • Epithelium
  • Genes
  • Prostate cancer

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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