From Grey Scale B-Mode to Elastosonography: Multimodal Ultrasound Imaging in Meningioma Surgery - Pictorial Essay and Literature Review

Francesco Prada, Massimiliano Del Bene, Alessandro Moiraghi, Cecilia Casali, Federico Giuseppe Legnani, Andrea Saladino, Alessandro Perin, Ignazio Gaspare Vetrano, Luca Mattei, Carla Richetta, Marco Saini, Francesco DiMeco

Research output: Contribution to journalArticle


The main goal in meningioma surgery is to achieve complete tumor removal, when possible, while improving or preserving patient neurological functions. Intraoperative imaging guidance is one fundamental tool for such achievement. In this regard, intra-operative ultrasound (ioUS) is a reliable solution to obtain real-time information during surgery and it has been applied in many different aspect of neurosurgery. In the last years, different ioUS modalities have been described: B-mode, Fusion Imaging with pre-operative acquired MRI, Doppler, contrast enhanced ultrasound (CEUS), and elastosonography. In this paper, we present our US based multimodal approach in meningioma surgery. We describe all the most relevant ioUS modalities and their intraoperative application to obtain precise and specific information regarding the lesion for a tailored approach in meningioma surgery. For each modality, we perform a review of the literature accompanied by a pictorial essay based on our routinely use of ioUS for meningioma resection.

Original languageEnglish
Article number925729
JournalBioMed Research International
Publication statusPublished - 2015


ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

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