Abstract
| Original language | English |
|---|---|
| Article number | 02402 |
| Journal | Frontiers in Immunology |
| Volume | 9 |
| DOIs | |
| Publication status | Published - 2018 |
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From mice to men: How B cell immunology helped the understanding of Leukemia development. / Ghia, P.
In: Frontiers in Immunology, Vol. 9, 02402, 2018.Research output: Contribution to journal › Article
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TY - JOUR
T1 - From mice to men: How B cell immunology helped the understanding of Leukemia development
AU - Ghia, P
PY - 2018
Y1 - 2018
N2 - The work on normal B lymphocytes, immunoglobulins, and antigenic stimulation performed at the Basel institute in the early '90s, also by Anton G. Rolink, shaped and molded the way B cell lymphomas and in particular Chronic Lymphocytic Leukemia (CLL) are interpreted today. Words like Immunoglobulin rearrangements, somatic mutations, and B Cell Receptors, which 25 years ago were of interest only to basic immunologists like Ton, became common and trivial (if ever possible) terms also in hematological and clinical gatherings. Nowadays immunologists are in fact regularly invited to such meetings as key-note speakers to explain the basic functionality of the immune system, which has direct implications on the daily clinical practice. © 2018 Frontiers Media S.A. All rights reserved.
AB - The work on normal B lymphocytes, immunoglobulins, and antigenic stimulation performed at the Basel institute in the early '90s, also by Anton G. Rolink, shaped and molded the way B cell lymphomas and in particular Chronic Lymphocytic Leukemia (CLL) are interpreted today. Words like Immunoglobulin rearrangements, somatic mutations, and B Cell Receptors, which 25 years ago were of interest only to basic immunologists like Ton, became common and trivial (if ever possible) terms also in hematological and clinical gatherings. Nowadays immunologists are in fact regularly invited to such meetings as key-note speakers to explain the basic functionality of the immune system, which has direct implications on the daily clinical practice. © 2018 Frontiers Media S.A. All rights reserved.
U2 - 10.3389/fimmu.2018.02402
DO - 10.3389/fimmu.2018.02402
M3 - Article
VL - 9
JO - Frontiers in Immunology
JF - Frontiers in Immunology
SN - 1664-3224
M1 - 02402
ER -