From phagocyte diversity and activation to probiotics: Back to Metchnikoff

Research output: Contribution to journalArticlepeer-review


In this issue of the European Journal of Immunology, Siamon Gordon gives a detailed account of Metchnikoff's life and his achievements (Eur. J. Immunol. 2008. 38: 3257-3264). Looking back at the roots of innate immunity stimulates reflections on open issues in the field. Here, I give a personal view of some of these issues, including myeloid-derived suppressor cells, macrophage polarization and adaptive responses of mononuclear phagocytes.

Original languageEnglish
Pages (from-to)3269-3273
Number of pages5
JournalEuropean Journal of Immunology
Issue number12
Publication statusPublished - 2008


  • M1/M2 polarization
  • Macrophage activation
  • Macrophages
  • Probiotics

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy


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