Dalla diagnosi prenatale al management post-natale delle malformazioni polmonari

Translated title of the contribution: From prenatal diagnosis to postnatal management of pulmonary malformations

F. Gobbo, G. Pelizzo, J. Schleef

Research output: Contribution to journalArticlepeer-review


Congenital pulmonary airway malformations (CPAM) include a wide spectrum of developmental anomalies. Almost 50% of the cases are diagnosed in utero. These appear as hyperechoic, cystic or mixed lesions. Prenatal clinical course varies from serious complications in utero to polyhydramnios with premature labor. Hydrops and fetal demise is reported in as many as 25-30% of cases. Postnatal presentation ranges from severe respiratory distress to symptoms related to pulmonary hypoplasia, left to right shunting in sequestration or overinflation and pneumothorax. When no prenatal diagnosis is made, children may remain asymptomatic or may present, later in their lives, with complications of recurrent pneumonias or spontaneous pneumothorax. Surgical resection represents the standard for symptomatic cases at birth and later in children with respiratory symptoms. Even though the management for asymptomatic cases remains controversial, early surgical excision to avoid recurrent infections, pneumothorax and malignancy is recommended. New instrumentation and advanced skills make thoracoscopic lobar lung resection the preferred approach.

Translated title of the contributionFrom prenatal diagnosis to postnatal management of pulmonary malformations
Original languageItalian
Pages (from-to)125
Number of pages1
JournalMedico e Bambino
Issue number2
Publication statusPublished - Feb 2010

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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