Frontiers in planning optimization for lung SBRT

F. R. Giglioli, S. Clemente, M. Esposito, C. Fiandra, C. Marino, S. Russo, L. Strigari, E. Villaggi, M. Stasi, P. Mancosu

Research output: Contribution to journalArticle

Abstract

Emerging data are showing the safety and the efficacy of Stereotactic Body Radiation therapy (SBRT) in lung cancer management. In this context, the very high doses delivered to the Planning Target Volume, make the planning phase essential for achieving high dose levels conformed to the shape of the target in order to have a good prognosis for tumor control and to avoid an overdose in relevant healthy adjacent tissue. In this non-systematic review we analyzed the technological and the physics aspects of SBRT planning for lung cancer. In particular, the aims of the study were: (i) to evaluate prescription strategies (homogeneous or inhomogeneous), (ii) to outline possible geometrical solutions by comparing the dosimetric results (iii) to describe the technological possibilities for a safe and effective treatment, (iv) to present the issues concerning radiobiological planning and the automation of the planning process.
Original languageEnglish
Pages (from-to)163-170
JournalPhysica Medica
Volume44
DOIs
Publication statusPublished - May 26 2017

Fingerprint

lungs
planning
radiation therapy
Lung Neoplasms
Radiotherapy
Lung
optimization
Automation
Physics
Prescriptions
Safety
cancer
dosage
prognosis
Neoplasms
automation
emerging
safety
tumors
Therapeutics

Keywords

  • Lung
  • Planning
  • Stereotactic Body Radiation Therapy (SBRT)
  • Stereotactic ablative radiotherapy (SABR)

Cite this

Giglioli, F. R., Clemente, S., Esposito, M., Fiandra, C., Marino, C., Russo, S., ... Mancosu, P. (2017). Frontiers in planning optimization for lung SBRT. Physica Medica, 44, 163-170. https://doi.org/S1120-1797(17)30180-1 [pii]

Frontiers in planning optimization for lung SBRT. / Giglioli, F. R.; Clemente, S.; Esposito, M.; Fiandra, C.; Marino, C.; Russo, S.; Strigari, L.; Villaggi, E.; Stasi, M.; Mancosu, P.

In: Physica Medica, Vol. 44, 26.05.2017, p. 163-170.

Research output: Contribution to journalArticle

Giglioli, FR, Clemente, S, Esposito, M, Fiandra, C, Marino, C, Russo, S, Strigari, L, Villaggi, E, Stasi, M & Mancosu, P 2017, 'Frontiers in planning optimization for lung SBRT', Physica Medica, vol. 44, pp. 163-170. https://doi.org/S1120-1797(17)30180-1 [pii]
Giglioli FR, Clemente S, Esposito M, Fiandra C, Marino C, Russo S et al. Frontiers in planning optimization for lung SBRT. Physica Medica. 2017 May 26;44:163-170. https://doi.org/S1120-1797(17)30180-1 [pii]
Giglioli, F. R. ; Clemente, S. ; Esposito, M. ; Fiandra, C. ; Marino, C. ; Russo, S. ; Strigari, L. ; Villaggi, E. ; Stasi, M. ; Mancosu, P. / Frontiers in planning optimization for lung SBRT. In: Physica Medica. 2017 ; Vol. 44. pp. 163-170.
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