Fronto-temporal vulnerability to disconnection in paediatric moderate and severe traumatic brain injury: European Journal of Neurology

E Molteni, E Pagani, S Strazzer, F Arrigoni, E Beretta, G Boffa, S Galbiati, M Filippi, MA Rocca

Research output: Contribution to journalArticle

Abstract

Background: In patients with moderate and severe paediatric traumatic brain injury (TBI), we investigated the presence and severity of white matter (WM) tract damage, cortical lobar and deep grey matter (GM) atrophies, their interplay and their correlation with outcome rating scales. Methods: Diffusion tensor (DT) and 3D T1-weighted MRI scans were obtained from 22 TBI children (13 boys; mean age at insult = 11.6 years; 72.7% in chronic condition) and 31 age-matched healthy children. Patients were tested with outcome rating scales and the Wechsler Intelligence Scale for Children (WISC). DT MRI indices were obtained from several supra- and infra-tentorial WM tracts. Cortical lobar and deep GM volumes were derived. Comparisons between patients and controls, and between patients in acute (
Original languageEnglish
Pages (from-to)1183-1190
Number of pages8
JournalEur. J. Neurol.
Volume26
Issue number9
DOIs
Publication statusPublished - 2019

Fingerprint Dive into the research topics of 'Fronto-temporal vulnerability to disconnection in paediatric moderate and severe traumatic brain injury: European Journal of Neurology'. Together they form a unique fingerprint.

  • Cite this