Frontotemporal dementia misdiagnosed for post-treatment lyme disease syndrome or vice versa? A treviso dementia (TREDEM) registry case report

Maria Elena Di Battista, Carola Dell'Acqua, Luciana Baroni, Chiara Fenoglio, Daniela Galimberti, Maurizio Gallucci

Research output: Contribution to journalArticle

Abstract

We describe the case of a 61-year-old woman diagnosed with Borreliosis at the age of 57. Subsequently, the patient developed depression, anxiety, and behavioral disturbances. A lumbar puncture excluded the condition of Neuroborreliosis. The diagnostic workup included: an MRI scan, a 18 F-FDG PET, a 123 I-ioflupane-SPECT, an amyloid-β PET, a specific genetic analysis, and a neuropsychological evaluation. Based on our investigation, the patient was diagnosed with probable behavioral-frontotemporal dementia (bvFTD), whereas in the previous years, the patient had been considered firstly as a case of Post-Treatment-Lyme Disease and, secondly, a psychiatric patient. We believe that, in the present case, such initial symptoms of Borrelia infection may have superimposed on those of bvFTD rather than playing as a contributory cause.

Original languageEnglish
Pages (from-to)445-451
Number of pages7
JournalJournal of Alzheimer's Disease
Volume66
Issue number2
DOIs
Publication statusPublished - Jan 1 2018

Keywords

  • Borrelia
  • depression
  • frontotemporal dementia
  • Lyme disease
  • misdiagnosis
  • post-treatment Lyme disease

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Psychology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

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