Full in-beam PET measurements of 62 MeV protons onto a PMMA target

G. Sportelli, K. Straub, M. Aiello, F. Attanasi, N. Belcari, N. Camarlinghi, G. A P Cirrone, G. Cuttone, S. Ferretti, N. Marino, D. Nicolosi, F. Romano, V. Rosso, A. Del Guerra

Research output: Contribution to journalArticle

Abstract

Positron emission tomography (PET) is a valuable technique to monitor in situ and non-invasively the particle range in ion beam therapy exploiting the beta+ activity produced in nuclear interactions along the beam path within the target volume. Due to the high random rates and dead-time losses induced by the particle spills, as of to date data are usually acquired during beam pauses or after the irradiation. We have developed a new PET prototype with a faster photon discrimination component that reduces the front-end dead time, and a modularized acquisition system that parallelizes the sensitive detector area, so as to enable data acquisition also during therapeutic irradiation (full in-beam measurement). The PET system has been able to sustain the single photon count rates and acquire coincidences during the beam, in conditions of sub-clinical beam currents. A study on the paralyzation conditions and dead time losses under different beam currents is presented and the feasibility of a full in-beam PET scanner is discussed.

Original languageEnglish
Pages (from-to)151-153
Number of pages3
JournalNuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Volume718
DOIs
Publication statusPublished - 2013

Keywords

  • In-beam monitoring
  • PET
  • Proton therapy

ASJC Scopus subject areas

  • Instrumentation
  • Nuclear and High Energy Physics

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    Sportelli, G., Straub, K., Aiello, M., Attanasi, F., Belcari, N., Camarlinghi, N., Cirrone, G. A. P., Cuttone, G., Ferretti, S., Marino, N., Nicolosi, D., Romano, F., Rosso, V., & Del Guerra, A. (2013). Full in-beam PET measurements of 62 MeV protons onto a PMMA target. Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 718, 151-153. https://doi.org/10.1016/j.nima.2012.08.100