Fulminant Versus Acute Nonfulminant Myocarditis in Patients With Left Ventricular Systolic Dysfunction: Journal of the American College of Cardiology

E Ammirati, G Veronese, M Brambatti, M Merlo, M Cipriani, L Potena, P Sormani, T Aoki, K Sugimura, A Sawamura, T Okumura, S Pinney, K Hong, P Shah, Ö Braun, CM Van de Heyning, S Montero, D Petrella, F Huang, M SchmidtC Raineri, A Lala, M Varrenti, A Foà, O Leone, P Gentile, J Artico, V Agostini, R Patel, A Garascia, EM Van Craenenbroeck, K Hirose, A Isotani, T Murohara, Y Arita, A Sionis, E Fabris, S Hashem, V Garcia-Hernando, F Oliva, B Greenberg, H Shimokawa, G Sinagra, ED Adler, M Frigerio, PG Camici

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Fulminant myocarditis (FM) is a form of acute myocarditis characterized by severe left ventricular systolic dysfunction requiring inotropes and/or mechanical circulatory support. A single-center study found that a patient with FM had better outcomes than those with acute nonfulminant myocarditis (NFM) presenting with left ventricular systolic dysfunction, but otherwise hemodynamically stable. This was recently challenged, so disagreement still exists. Objectives: This study sought to provide additional evidence on the outcome of FM and to ascertain whether patient stratification based on the main histologic subtypes can provide additional prognostic information. Methods: A total of 220 patients (median age 42 years, 46.3% female) with histologically proven acute myocarditis (onset of symptoms
Original languageEnglish
Pages (from-to)299-311
Number of pages13
JournalJournal of the American College of Cardiology
Volume74
Issue number3
DOIs
Publication statusPublished - 2019

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