Funzionalità e complicanze di diversi sistemi totalmente impiantabili per l'infusione intraarteriosa continua di FUdR nelle metastasi epatiche colo-rettali.

Translated title of the contribution: Function and complications of diverse totally implantable systems for continuous intra-arterial infusion of FUdR in colorectal hepatic metastases

D. Civalleri, P. Bignami, F. De Cian, M. Cosimelli, G. Simoni, N. Balletto, G. Mondini, S. Carrabetta

Research output: Contribution to journalArticle

Abstract

Different totally implantable arterial infusion systems were compared in patients with liver metastases from colorectal cancer undergoing continuous intra-arterial infusion. Seventy-eight patients received continuous FUdR infusion using either totally implantable pumps (group a = 44 pts.) or ports fed by external portable pumps (group b = 34 pts.), and 57 patients received bolus infusion of Cisplatin (group c). Devices were cared for patency even after interruption of treatment, commonly caused by disease progression. Pocket problems most frequently occurred in group a (30%) compared to groups b (9%) and c (7%), whereas a higher incidence of catheter and infusion related problems was observed in group b (109%). System failure was recorded as a cause of interruption of treatment in two, 9, and 6 cases in groups a to c, respectively. The 12-months patency rate was 92% in group a, 24% in group b (median 9 months), and 65% in group c (median 17 months). Though implantable ports allow adequate infusion periods in most cases they seem more adequate for bolus infusions.

Translated title of the contributionFunction and complications of diverse totally implantable systems for continuous intra-arterial infusion of FUdR in colorectal hepatic metastases
Original languageItalian
Pages (from-to)309-313
Number of pages5
JournalGiornale di Chirurgia
Volume17
Issue number6-7
Publication statusPublished - Jun 1996

ASJC Scopus subject areas

  • Surgery

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    Civalleri, D., Bignami, P., De Cian, F., Cosimelli, M., Simoni, G., Balletto, N., Mondini, G., & Carrabetta, S. (1996). Funzionalità e complicanze di diversi sistemi totalmente impiantabili per l'infusione intraarteriosa continua di FUdR nelle metastasi epatiche colo-rettali. Giornale di Chirurgia, 17(6-7), 309-313.