Functional assessment and Quality of Life before and after Pulmonary Endoarterectomy

Lucia Petrucci, Ettore Carlisi, Susanna Ricotti, Simona Zanellato, Catherine Klersy, Andrea M. D'Armini, Salvatore Nicolardi, Marco Morsolini, Mario Viganò, Elena Dalla Toffola

Research output: Contribution to journalArticlepeer-review


Purpose: The study investigates Quality of Life (QOL) and correlation with functional status of patients affected by Chronic Thromboembolic Pulmonary Hypertension who undergo Pulmonary Endoarterectomy. Methods: We investigated with an observational design (before surgery, three and twelve months afterwards) the hemodynamic data (NYHA class, mean pulmonary arterial pressure, cardiac output and pulmonary vascular resistance), the functional status (using the 6-Minute Walk Test) and the QOL, using three questionnaires: Medical Outcome Study Short Form-36 (SF-36), Minnesota Living with Heart Failure Questionnaire (MLHFQ), Saint George Respiratory Questionnaire (SGRQ). We report the results of forty-nine patients. Results: After surgery there was an improvement on functional and hemodynamic parameters and on QOL. The physical domain (PCS) of SF-36 was weakly but significantly associated with all functional parameters. There was no association between functional parameters and mental domain (MCS) of SF-36 or SGRQ. The improvement in 6-Minute Walk Distance was associated with an increase in MLHFQ. Conclusions: Both QOL and submaximal exercise tolerance improve after surgery. However only the physical domains of SF-36 appear to be significantly associated to the functional data.

Original languageEnglish
Pages (from-to)170-175
Number of pages6
JournalGiornale Italiano di Medicina del Lavoro ed Ergonomia
Issue number3
Publication statusPublished - Jul 1 2015


  • Pulmonary Endoarterectomy
  • Pulmonary Hypertension
  • Quality of Life
  • Rehabilitation
  • Six Minute Walk Test

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


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