Functional assessment of a new extended depth-of-focus intraocular lens

Giacomo Savini, Nicole Balducci, Claudio Carbonara, Scipione Rossi, Manuel Altieri, Nicola Frugis, Emilia Zappulla, Roberto Bellucci, Giovanni Alessio

Research output: Contribution to journalArticle

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Abstract

Background/objective: This study aimed to investigate the visual performance of a new extended depth-of-focus intraocular lens (EDOF-IOL). Subjects/methods: In this multicenter, prospective, observational study, we enrolled 97 patients who underwent cataract surgery or refractive lens exchange with implantation of the Mini Well EDOF-IOL (SIFI, Italy). Patients underwent postoperatively the following examinations between 4 and 8 weeks after surgery: corrected distance visual acuity (CDVA), reading speed with Radner’s chart, distance-corrected near visual acuity (DCNVA), defocus curve, contrast sensitivity, and haloes quantitative assessment. Results: In the whole sample, the mean monocular CDVA and DCNVA were, respectively, 0.02 ± 0.07 logMAR and 0.38 ± 0.15 logRAD (logarithm of the reading acuity determination). In the 67 bilaterally implanted patients, binocular CDVA and DCNVA were better (0.00 ± 0.05 logMAR and 0.26 ± 0.13 logRAD) than the corresponding monocular values (p = 0.02 and p = 0.0002, respectively). Ninety-two percent of patients bilaterally implanted reached a binocular reading speed >80 words per minute at a 0.5 logRAD print size (corresponding to the common book print size). The defocus curves showed that the EDOF-IOL provided increased depth of focus through 2.0 D of defocus, with the best performance at 1.0 and 1.5 D. Contrast sensitivity was within normal limits at all spatial frequencies. The mean visual disturbance index was 0.08 ± 0.12, suggesting low night visual disturbances. Conclusions: The new EDOF-IOL provided good visual acuity for distance, intermediate, and near vision, with no loss of contrast sensitivity and low risk of night visual disturbances.

Original languageEnglish
JournalEye (Basingstoke)
DOIs
Publication statusE-pub ahead of print - Sep 28 2018

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Intraocular Lenses
Visual Acuity
Reading
Contrast Sensitivity
Refractive Surgical Procedures
Cataract
Italy
Lenses
Observational Studies
Prospective Studies

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

Cite this

Savini, G., Balducci, N., Carbonara, C., Rossi, S., Altieri, M., Frugis, N., ... Alessio, G. (2018). Functional assessment of a new extended depth-of-focus intraocular lens. Eye (Basingstoke). https://doi.org/10.1038/s41433-018-0221-1

Functional assessment of a new extended depth-of-focus intraocular lens. / Savini, Giacomo; Balducci, Nicole; Carbonara, Claudio; Rossi, Scipione; Altieri, Manuel; Frugis, Nicola; Zappulla, Emilia; Bellucci, Roberto; Alessio, Giovanni.

In: Eye (Basingstoke), 28.09.2018.

Research output: Contribution to journalArticle

Savini, G, Balducci, N, Carbonara, C, Rossi, S, Altieri, M, Frugis, N, Zappulla, E, Bellucci, R & Alessio, G 2018, 'Functional assessment of a new extended depth-of-focus intraocular lens', Eye (Basingstoke). https://doi.org/10.1038/s41433-018-0221-1
Savini, Giacomo ; Balducci, Nicole ; Carbonara, Claudio ; Rossi, Scipione ; Altieri, Manuel ; Frugis, Nicola ; Zappulla, Emilia ; Bellucci, Roberto ; Alessio, Giovanni. / Functional assessment of a new extended depth-of-focus intraocular lens. In: Eye (Basingstoke). 2018.
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