Functional connectivity between posterior hippocampus and retrosplenial complex predicts individual differences in navigational ability

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Individuals vary widely in their ability to orient and navigate within the environment. Previous neuroimaging research has shown that hippocampus (HC) and scene-responsive regions (retrosplenial complex [RSC] and parahippocampal gyrus/parahippocampal place area [PPA]) were crucial for spatial orienting and navigation. Resting-state functional connectivity and a self-reported questionnaire of navigational ability were used to examine the hypothesis that the pattern of reciprocal connections between these regions reflects individual differences in spatial navigation. It was found that the functional connectivity between the posterior HC and RSC was significantly higher in good than in poor navigators. These results confirmed the crucial role of hippocampal and extra-hippocampal regions in spatial navigation and provided new insight into how spontaneous brain activity may account for individual differences in spatial ability.

Original languageEnglish
Pages (from-to)841-847
Number of pages7
JournalHippocampus
Volume26
Issue number7
DOIs
Publication statusPublished - Jul 1 2016

Fingerprint

Aptitude
Individuality
Hippocampus
Parahippocampal Gyrus
Neuroimaging
Spatial Navigation
Brain
Research

Keywords

  • gender-differences
  • resting-state connectivity
  • scene-responsive regions
  • seed-to-seed correlations
  • self-reported spatial ability

ASJC Scopus subject areas

  • Cognitive Neuroscience

Cite this

@article{deffc6430ec54aa19f3ae7dc46cd061c,
title = "Functional connectivity between posterior hippocampus and retrosplenial complex predicts individual differences in navigational ability",
abstract = "Individuals vary widely in their ability to orient and navigate within the environment. Previous neuroimaging research has shown that hippocampus (HC) and scene-responsive regions (retrosplenial complex [RSC] and parahippocampal gyrus/parahippocampal place area [PPA]) were crucial for spatial orienting and navigation. Resting-state functional connectivity and a self-reported questionnaire of navigational ability were used to examine the hypothesis that the pattern of reciprocal connections between these regions reflects individual differences in spatial navigation. It was found that the functional connectivity between the posterior HC and RSC was significantly higher in good than in poor navigators. These results confirmed the crucial role of hippocampal and extra-hippocampal regions in spatial navigation and provided new insight into how spontaneous brain activity may account for individual differences in spatial ability.",
keywords = "gender-differences, resting-state connectivity, scene-responsive regions, seed-to-seed correlations, self-reported spatial ability",
author = "Valentina Sulpizio and Maddalena Boccia and Cecilia Guariglia and Gaspare Galati",
year = "2016",
month = "7",
day = "1",
doi = "10.1002/hipo.22592",
language = "English",
volume = "26",
pages = "841--847",
journal = "Hippocampus",
issn = "1050-9631",
publisher = "Wiley-Liss Inc.",
number = "7",

}

TY - JOUR

T1 - Functional connectivity between posterior hippocampus and retrosplenial complex predicts individual differences in navigational ability

AU - Sulpizio, Valentina

AU - Boccia, Maddalena

AU - Guariglia, Cecilia

AU - Galati, Gaspare

PY - 2016/7/1

Y1 - 2016/7/1

N2 - Individuals vary widely in their ability to orient and navigate within the environment. Previous neuroimaging research has shown that hippocampus (HC) and scene-responsive regions (retrosplenial complex [RSC] and parahippocampal gyrus/parahippocampal place area [PPA]) were crucial for spatial orienting and navigation. Resting-state functional connectivity and a self-reported questionnaire of navigational ability were used to examine the hypothesis that the pattern of reciprocal connections between these regions reflects individual differences in spatial navigation. It was found that the functional connectivity between the posterior HC and RSC was significantly higher in good than in poor navigators. These results confirmed the crucial role of hippocampal and extra-hippocampal regions in spatial navigation and provided new insight into how spontaneous brain activity may account for individual differences in spatial ability.

AB - Individuals vary widely in their ability to orient and navigate within the environment. Previous neuroimaging research has shown that hippocampus (HC) and scene-responsive regions (retrosplenial complex [RSC] and parahippocampal gyrus/parahippocampal place area [PPA]) were crucial for spatial orienting and navigation. Resting-state functional connectivity and a self-reported questionnaire of navigational ability were used to examine the hypothesis that the pattern of reciprocal connections between these regions reflects individual differences in spatial navigation. It was found that the functional connectivity between the posterior HC and RSC was significantly higher in good than in poor navigators. These results confirmed the crucial role of hippocampal and extra-hippocampal regions in spatial navigation and provided new insight into how spontaneous brain activity may account for individual differences in spatial ability.

KW - gender-differences

KW - resting-state connectivity

KW - scene-responsive regions

KW - seed-to-seed correlations

KW - self-reported spatial ability

UR - http://www.scopus.com/inward/record.url?scp=84975048632&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84975048632&partnerID=8YFLogxK

U2 - 10.1002/hipo.22592

DO - 10.1002/hipo.22592

M3 - Article

VL - 26

SP - 841

EP - 847

JO - Hippocampus

JF - Hippocampus

SN - 1050-9631

IS - 7

ER -