Functional disability in early Alzheimer's disease - A validation study of the Italian version of the Disability Assessment for Dementia scale

Luc Pieter De Vreese, Paolo Caffarra, Rita Savarè, Renata Cerutti, Massimo Franceschi, Enzo Grossi, M. Alberoni, A. Cester, M. Gallucci, M. V. Giannelli, P. Mecocci, A. Padovani, R. Perri, C. Pettenati, A. Stracciari, M. Neri

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: To determine the applicability and psychometric properties of the Italian version of the Disability Assessment of Dementia scale (DAD-I) in a community-residing population with early-stage Alzheimer's disease (AD). Methods: The DAD-I was administered to the primary caregivers of 159 patients (mean age ± SD 77.1 ± 5.2) with mild AD (mean Mini Mental State Examination, MMSE, ± SD 23.1 ± 2.2). Results: The DAD-I showed excellent internal consistency reliability (Cronbach's α = 0.92) and good construct validity. The DAD-I score was not significantly associated with gender, education and presumed duration of the illness, and had a low negative correlation with age. The DAD-I score correlated moderately with the traditional Instrumental Activities of Daily Living and Activities of Daily Living scales, respectively, with r = 0.53 and r = 0.54 (p <0.0001). Relatively low, but statistically significant correlations (r ranging between 0.21 and 0.31) with the MMSE were also found. Conclusion: The DAD-I was found to be a reliable and valid instrument to assess functional disability in community-dwelling Italian subjects with early-stage AD.

Original languageEnglish
Pages (from-to)186-194
Number of pages9
JournalDementia and Geriatric Cognitive Disorders
Volume25
Issue number2
DOIs
Publication statusPublished - Feb 2008

Keywords

  • Alzheimer's disease, functional disability
  • Disability Assessment for Dementia
  • Psychometric properties

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Geriatrics and Gerontology

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