Functional evaluation of Duchenne muscular dystrophy: Proposal for a protocol

F. Cornelio, F. Dworzak, L. Morandi, E. Fedrizzi, M. R. Balestrini, L. Gondoni

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A protocol for the evaluation of functional activities in subjects with Duchenne muscular dystrophy (DMD) was designed. The aim of our study was to define objective clinical criteria for the evaluation both of the clinical status of the patient and of the natural history of the illness itself. A protocol with such criteria is particularly necessary when testing the efficacy of treatment. 43 still-ambulant children with DMD between the ages of 3.10 yr and 10.4 yr were examined. Of this number 19 children were evaluated every 4 months over a period of 12 months; of these 14 formed part of a randomized double blind trial with L-carnitine (1.2-1.8 g/day) versus placebo.

Original languageEnglish
Pages (from-to)323-330
Number of pages8
JournalItalian Journal of Neurological Sciences
Volume3
Issue number4
DOIs
Publication statusPublished - Dec 1982

Fingerprint

Duchenne Muscular Dystrophy
Carnitine
Natural History
Placebos

Keywords

  • Duchenne muscular dystrophy
  • functional evaluation

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

Cite this

Cornelio, F., Dworzak, F., Morandi, L., Fedrizzi, E., Balestrini, M. R., & Gondoni, L. (1982). Functional evaluation of Duchenne muscular dystrophy: Proposal for a protocol. Italian Journal of Neurological Sciences, 3(4), 323-330. https://doi.org/10.1007/BF02043581

Functional evaluation of Duchenne muscular dystrophy : Proposal for a protocol. / Cornelio, F.; Dworzak, F.; Morandi, L.; Fedrizzi, E.; Balestrini, M. R.; Gondoni, L.

In: Italian Journal of Neurological Sciences, Vol. 3, No. 4, 12.1982, p. 323-330.

Research output: Contribution to journalArticle

Cornelio, F, Dworzak, F, Morandi, L, Fedrizzi, E, Balestrini, MR & Gondoni, L 1982, 'Functional evaluation of Duchenne muscular dystrophy: Proposal for a protocol', Italian Journal of Neurological Sciences, vol. 3, no. 4, pp. 323-330. https://doi.org/10.1007/BF02043581
Cornelio, F. ; Dworzak, F. ; Morandi, L. ; Fedrizzi, E. ; Balestrini, M. R. ; Gondoni, L. / Functional evaluation of Duchenne muscular dystrophy : Proposal for a protocol. In: Italian Journal of Neurological Sciences. 1982 ; Vol. 3, No. 4. pp. 323-330.
@article{7afa8457402e4e96a32be7074273972d,
title = "Functional evaluation of Duchenne muscular dystrophy: Proposal for a protocol",
abstract = "A protocol for the evaluation of functional activities in subjects with Duchenne muscular dystrophy (DMD) was designed. The aim of our study was to define objective clinical criteria for the evaluation both of the clinical status of the patient and of the natural history of the illness itself. A protocol with such criteria is particularly necessary when testing the efficacy of treatment. 43 still-ambulant children with DMD between the ages of 3.10 yr and 10.4 yr were examined. Of this number 19 children were evaluated every 4 months over a period of 12 months; of these 14 formed part of a randomized double blind trial with L-carnitine (1.2-1.8 g/day) versus placebo.",
keywords = "Duchenne muscular dystrophy, functional evaluation",
author = "F. Cornelio and F. Dworzak and L. Morandi and E. Fedrizzi and Balestrini, {M. R.} and L. Gondoni",
year = "1982",
month = "12",
doi = "10.1007/BF02043581",
language = "English",
volume = "3",
pages = "323--330",
journal = "Italian Journal of Neurological Sciences",
issn = "0392-0461",
publisher = "Springer Verlag",
number = "4",

}

TY - JOUR

T1 - Functional evaluation of Duchenne muscular dystrophy

T2 - Proposal for a protocol

AU - Cornelio, F.

AU - Dworzak, F.

AU - Morandi, L.

AU - Fedrizzi, E.

AU - Balestrini, M. R.

AU - Gondoni, L.

PY - 1982/12

Y1 - 1982/12

N2 - A protocol for the evaluation of functional activities in subjects with Duchenne muscular dystrophy (DMD) was designed. The aim of our study was to define objective clinical criteria for the evaluation both of the clinical status of the patient and of the natural history of the illness itself. A protocol with such criteria is particularly necessary when testing the efficacy of treatment. 43 still-ambulant children with DMD between the ages of 3.10 yr and 10.4 yr were examined. Of this number 19 children were evaluated every 4 months over a period of 12 months; of these 14 formed part of a randomized double blind trial with L-carnitine (1.2-1.8 g/day) versus placebo.

AB - A protocol for the evaluation of functional activities in subjects with Duchenne muscular dystrophy (DMD) was designed. The aim of our study was to define objective clinical criteria for the evaluation both of the clinical status of the patient and of the natural history of the illness itself. A protocol with such criteria is particularly necessary when testing the efficacy of treatment. 43 still-ambulant children with DMD between the ages of 3.10 yr and 10.4 yr were examined. Of this number 19 children were evaluated every 4 months over a period of 12 months; of these 14 formed part of a randomized double blind trial with L-carnitine (1.2-1.8 g/day) versus placebo.

KW - Duchenne muscular dystrophy

KW - functional evaluation

UR - http://www.scopus.com/inward/record.url?scp=0020420397&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020420397&partnerID=8YFLogxK

U2 - 10.1007/BF02043581

DO - 10.1007/BF02043581

M3 - Article

C2 - 6762370

AN - SCOPUS:0020420397

VL - 3

SP - 323

EP - 330

JO - Italian Journal of Neurological Sciences

JF - Italian Journal of Neurological Sciences

SN - 0392-0461

IS - 4

ER -