Abstract
Sixteen patients underwent evaluation of duodenogastric reflux and gastric function 1 to 7 years after esophagectomy, high intrathoracic anastomosis, and pyloric divulsion for esophageal cancer. Ten patients (62%) had either postoperative digestive symptoms or endoscopic mucosal lesions, cholescintigraphy demonstrated duodenogastric reflux in 11 cases (69%). No gastric motor activity was recorded on manometry. 24-hour pH gastric monitoring showed that the area under the curve less than 4 was significantly less than in controls (p = 0.0003). The results of the present study show that duodenogastric reflux is a common event after esophageal replacement with the stomach. The interaction between acid and alkaline secretions plays a role in the pathogenesis of mucosal lesions, and it may explain the partial failure of the current therapeutic strategies.
| Original language | Italian |
|---|---|
| Pages (from-to) | 247-251 |
| Number of pages | 5 |
| Journal | Minerva Chirurgica |
| Volume | 46 |
| Issue number | 7 Suppl |
| Publication status | Published - Apr 15 1991 |
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ASJC Scopus subject areas
- Surgery
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Valutazione funzionale del paziente operato di esofagectomia ed esofagogastroplastica intratoracica per cancro dell'esofago. / Bonavina, L.; Anselmino, M.; Ruol, A.; Borsato, N.; Peracchia, A.
In: Minerva Chirurgica, Vol. 46, No. 7 Suppl, 15.04.1991, p. 247-251.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Valutazione funzionale del paziente operato di esofagectomia ed esofagogastroplastica intratoracica per cancro dell'esofago.
AU - Bonavina, L.
AU - Anselmino, M.
AU - Ruol, A.
AU - Borsato, N.
AU - Peracchia, A.
PY - 1991/4/15
Y1 - 1991/4/15
N2 - Sixteen patients underwent evaluation of duodenogastric reflux and gastric function 1 to 7 years after esophagectomy, high intrathoracic anastomosis, and pyloric divulsion for esophageal cancer. Ten patients (62%) had either postoperative digestive symptoms or endoscopic mucosal lesions, cholescintigraphy demonstrated duodenogastric reflux in 11 cases (69%). No gastric motor activity was recorded on manometry. 24-hour pH gastric monitoring showed that the area under the curve less than 4 was significantly less than in controls (p = 0.0003). The results of the present study show that duodenogastric reflux is a common event after esophageal replacement with the stomach. The interaction between acid and alkaline secretions plays a role in the pathogenesis of mucosal lesions, and it may explain the partial failure of the current therapeutic strategies.
AB - Sixteen patients underwent evaluation of duodenogastric reflux and gastric function 1 to 7 years after esophagectomy, high intrathoracic anastomosis, and pyloric divulsion for esophageal cancer. Ten patients (62%) had either postoperative digestive symptoms or endoscopic mucosal lesions, cholescintigraphy demonstrated duodenogastric reflux in 11 cases (69%). No gastric motor activity was recorded on manometry. 24-hour pH gastric monitoring showed that the area under the curve less than 4 was significantly less than in controls (p = 0.0003). The results of the present study show that duodenogastric reflux is a common event after esophageal replacement with the stomach. The interaction between acid and alkaline secretions plays a role in the pathogenesis of mucosal lesions, and it may explain the partial failure of the current therapeutic strategies.
UR - http://www.scopus.com/inward/record.url?scp=0026424752&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026424752&partnerID=8YFLogxK
M3 - Articolo
VL - 46
SP - 247
EP - 251
JO - Minerva Chirurgica
JF - Minerva Chirurgica
SN - 0026-4733
IS - 7 Suppl
ER -