Functional magnetic resonance imaging correlates of cognitive performance in patients with a clinically isolated syndrome suggestive of multiple sclerosis at presentation: An activation and connectivity study

C. Forn, M. A. Rocca, P. Valsasina, I. Boscá, B. Casanova, A. Sanjuan, C. Ávila, M. Filippi

Research output: Contribution to journalArticle

Abstract

Background/Objective: To assess whether abnormalities on functional magnetic resonance imaging (fMRI) are related to cognitive function in patients at presentation with clinically isolated syndrome (CIS) suggestive of multiple sclerosis. Methods: Eighteen patients with CIS and 15 healthy controls (HCs) performed an adapted fMRI version of the Paced Auditory Serial Addition Test (PASAT). According to their PASAT performance, CIS patients were divided into two groups: 10 with a low PASAT performance (

Original languageEnglish
Pages (from-to)153-163
Number of pages11
JournalMultiple Sclerosis Journal
Volume18
Issue number2
DOIs
Publication statusPublished - 2012

Keywords

  • MRI
  • multiple sclerosis
  • T2 lesions

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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