Functional magnetic resonance imaging in multiple sclerosis

Tarek Ahmed Yousry, Isabelle Berry, Massimo Filippi

Research output: Contribution to journalArticlepeer-review


Functional magnetic resonance imaging (fMRI) is a method that combines high anatomical spatial resolution with the ability to localise function. Visual and motor systems are among those that have received most attention. Yet the clinical application is still limited. Recently, some investigators applied fMRI to study patients with multiple sclerosis. Patients with partial motor weakness disclosed a larger area of cortical activation bilaterally by contrast with healthy volunteers when using the affected arm, whereas patients with optical neuritis disclosed a smaller area of activation, when stimulating the affected eye. These results show that different systems might react heterogeneously.

Original languageEnglish
JournalJournal of Neurology, Neurosurgery and Psychiatry
Issue numberSUPPL. 1
Publication statusPublished - May 1998


  • Functional magnetic resonance imaging
  • Motor cortex
  • Multiple sclerosis

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology


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