Functional MRI of the human brain with GRASE-based BOLD contrast

Jorge Jovicich, David G. Norris

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The application of T2*-weighted gradient and spin-echo (GRASE) imaging was investigated as a method for blood oxygenation level-dependent (BOLD)- based functional magnetic resonance imaging (fMRI). The displaced-echo method was implemented to produce single-shot T2*-weighted GRASE images. This technique removes the requirement that the Carr-Purcell Meiboom-Gill (CPMG) condition be fulfilled. T2*-weighted GRASE images that are free from interference artifacts can thus be obtained, hence allowing the possibility of using single-shot GRASE for BOLD-based functional imaging. The method was demonstrated at 3 T and gave robust and reproducible activation-induced signal changes.

Original languageEnglish
Pages (from-to)871-876
Number of pages6
JournalMagnetic Resonance in Medicine
Volume41
Issue number5
DOIs
Publication statusPublished - 1999

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Magnetic Resonance Imaging
Brain
Artifacts

Keywords

  • Displaced-echo
  • Functional MRI
  • GRASE imaging
  • Template interactive phase encoding

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Functional MRI of the human brain with GRASE-based BOLD contrast. / Jovicich, Jorge; Norris, David G.

In: Magnetic Resonance in Medicine, Vol. 41, No. 5, 1999, p. 871-876.

Research output: Contribution to journalArticle

Jovicich, Jorge ; Norris, David G. / Functional MRI of the human brain with GRASE-based BOLD contrast. In: Magnetic Resonance in Medicine. 1999 ; Vol. 41, No. 5. pp. 871-876.
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