Abstract
To probe the hypothesis of a role for a functionally relevant 44 bp insertion/deletion of the serotonin transporter promoter in the aetiopathogenesis of panic disorder, we determined the allele frequency of the variant in two samples (combined n = 158) of panic disorder patients (DSMIII-R) and compared it with its allele frequency in two ethnically matched control samples (combined n = 169). The fact that no difference could be observed (χ2 analysis) argues against a major role for this serotonin transporter promoter polymorphism in the aetiopathogenesis of panic disorder.
Original language | English |
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Pages (from-to) | 45-47 |
Number of pages | 3 |
Journal | Psychiatric Genetics |
Volume | 7 |
Issue number | 1 |
Publication status | Published - 1997 |
Keywords
- Panic disorder
- Promoter variant
- Serotonin transporter
ASJC Scopus subject areas
- Genetics(clinical)
- Psychiatry and Mental health
- Genetics
- Neuroscience(all)