Functional promoter polymorphism of the human serotonin transporter: Lack of association with panic disorder

J. Deckert, M. Catalano, A. Heils, D. Di Bella, F. Friess, E. Politi, P. Franke, M. M. Nöthen, W. Maier, L. Bellodi, K. P. Lesch

Research output: Contribution to journalArticlepeer-review

Abstract

To probe the hypothesis of a role for a functionally relevant 44 bp insertion/deletion of the serotonin transporter promoter in the aetiopathogenesis of panic disorder, we determined the allele frequency of the variant in two samples (combined n = 158) of panic disorder patients (DSMIII-R) and compared it with its allele frequency in two ethnically matched control samples (combined n = 169). The fact that no difference could be observed (χ2 analysis) argues against a major role for this serotonin transporter promoter polymorphism in the aetiopathogenesis of panic disorder.

Original languageEnglish
Pages (from-to)45-47
Number of pages3
JournalPsychiatric Genetics
Volume7
Issue number1
Publication statusPublished - 1997

Keywords

  • Panic disorder
  • Promoter variant
  • Serotonin transporter

ASJC Scopus subject areas

  • Genetics(clinical)
  • Psychiatry and Mental health
  • Genetics
  • Neuroscience(all)

Fingerprint

Dive into the research topics of 'Functional promoter polymorphism of the human serotonin transporter: Lack of association with panic disorder'. Together they form a unique fingerprint.

Cite this