Recupero funzionale dopo stroke e modificazioni del flusso ematico cerebrale durante attivita mentale

Translated title of the contribution: Functional recovery after stroke and cerebral blood flow changes during mental activity

M. Silvestrini, E. Troisi, P. Coiro, M. Matteis, B. C. Monaldo, C. Caltagirone

Research output: Contribution to journalArticle

Abstract

Our aim in this study was to investigate the correlations between cerebral hemodynamics and clinical course of aphasia in patients after stroke. Measurements of flow velocity were recorded in the middle cerebral arteries by means of bilateral transcranial Doppler ultrasonography during a rest period and during execution of a word-fluency task in 20 stroke patients with Broca's aphasia within 15 days from onset of symptoms and in 15 healthy controls. After two months, the patients were classified into two groups: absent or slight recovery (Group 1:8 patients) and good recovery (Group 2:12 patients). During the task the increase in flow velocity on the left side was similar in controls and in group 2 patients and, in both groups, significantly higher than in group 1 patients (p<.0001). Changes on the right side were slight and comparable in the three groups of the study subjects. These data suggest that the presence of an activation of areas in the lesioned hemisphere, soon after stroke onset, is a predictor of recovery from aphasia.

Translated title of the contributionFunctional recovery after stroke and cerebral blood flow changes during mental activity
Original languageItalian
Pages (from-to)133-136
Number of pages4
JournalRivista di Neurobiologia
Volume43
Issue number2-3
Publication statusPublished - 1997

ASJC Scopus subject areas

  • Neuroscience(all)

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    Silvestrini, M., Troisi, E., Coiro, P., Matteis, M., Monaldo, B. C., & Caltagirone, C. (1997). Recupero funzionale dopo stroke e modificazioni del flusso ematico cerebrale durante attivita mentale. Rivista di Neurobiologia, 43(2-3), 133-136.