ENVOLVIMENTO DA FUNCAO RENAL EM DOENTES NORMOTENSOS COM ESCLEROSE SISTEMICA PROGRESSIVA. ALTERACAO DA EXCRECAO DE SODIO DURANTE UMA PERFUSAO DE SORO ISOTONICO

Translated title of the contribution: Functional renal involvement in normotensive patients with progressive systemic sclerosis (Impaired sodium excretion during isotonic saline infusion)

A. D'Angelo, P. Messa, U. Fiocco

Research output: Contribution to journalArticlepeer-review

Abstract

An intravenous infusion of 2,000 ml isotonic saline was performed in 8 normotensive, normoreninemic patients with progressive systemic sclerosis. None of them had clinical evidence of renal disease. Total and proximal fractional excretion compared with that of 8 normal subjects. No correlation was found with para-aminohippurate (PAH) clearance values. Two years after this study was done, 4 patients developed arterial hypertension; interestingly, plasma-renin activity remained within the normal range. Reduced sodium excretion is suggested as having a pathogenetic role in the hypertension of progressive systemic sclerosis.

Translated title of the contributionFunctional renal involvement in normotensive patients with progressive systemic sclerosis (Impaired sodium excretion during isotonic saline infusion)
Original languagePortuguese
Pages (from-to)225-232
Number of pages8
JournalArquivos de Reumatologia e Doencas Osteo-Articulares
Volume3
Issue number6
Publication statusPublished - 1982

ASJC Scopus subject areas

  • Rheumatology

Fingerprint

Dive into the research topics of 'Functional renal involvement in normotensive patients with progressive systemic sclerosis (Impaired sodium excretion during isotonic saline infusion)'. Together they form a unique fingerprint.

Cite this