Several fungi are responsible of brain mycoses; in Italy, after the appearance of AIDS, cryptococcosis became the most frequent infection, while aspergillosis and cerebal candidiasis remain rare. After a review of the literature about clinical pictures and therapy of these mycoses, we report our experience on 25 patients affected with AIDS and cryptococcal meningoencephalitis. Our conclusions are the following: 1) diagnosis must be made as soon as possible to obtain a better therapeutic response and to shorten time of hospitalization; 2) a careful mycological monitoring is necessary either during acute infection, to decide when acute treatment must be stopped, or during the follow-up, to evaluate the efficacy of maintenance therapy; 3) maintenance therapy should be performed in all cases to prevent relapses.
|Translated title of the contribution||Fungal infections of central nervous system|
|Number of pages||14|
|Journal||Giornale di Malattie Infettive e Parassitarie|
|Publication status||Published - 1991|
ASJC Scopus subject areas