Fungus colonisation of pulmonary rheumatoid nodule

A. Cavazza, M. Paci, E. Turrini, R. Dallari, G. Rossi

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

This report describes a 69 year old woman, suffering from active rheumatoid arthritis since the age of 60 and presenting with severe dyspnoea and cough. A computed tomography scan of the chest showed multiple bilateral pulmonary nodules, sometimes cavitated, associated with reticular opacities and pleural effusion. A videothoracoscopic excision of a cavitated nodule was performed. Seven days after surgery, a right pneumothorax developed, and the patient died of septicaemia one month later. Microscopically, the excised nodule was composed of necrotic fibrinoid material with a peripheral rim of palisaded histiocytes, extending to the pleural surface and containing several fungal hyphae morphologically consistent with aspergillus. A diagnosis of pulmonary rheumatoid nodule with fungus colonisation was made. In the lung, fungus colonisation is a rare complication of rheumatoid nodules. The most important differential diagnostic considerations are briefly discussed.

Original languageEnglish
Pages (from-to)636-637
Number of pages2
JournalJournal of Clinical Pathology
Volume56
Issue number8
DOIs
Publication statusPublished - Aug 1 2003

Fingerprint

Rheumatoid Nodule
Fungi
Multiple Pulmonary Nodules
Lung
Histiocytes
Hyphae
Pneumothorax
Pleural Effusion
Aspergillus
Ambulatory Surgical Procedures
Cough
Dyspnea
Rheumatoid Arthritis
Sepsis
Thorax
Tomography

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Fungus colonisation of pulmonary rheumatoid nodule. / Cavazza, A.; Paci, M.; Turrini, E.; Dallari, R.; Rossi, G.

In: Journal of Clinical Pathology, Vol. 56, No. 8, 01.08.2003, p. 636-637.

Research output: Contribution to journalArticle

Cavazza, A. ; Paci, M. ; Turrini, E. ; Dallari, R. ; Rossi, G. / Fungus colonisation of pulmonary rheumatoid nodule. In: Journal of Clinical Pathology. 2003 ; Vol. 56, No. 8. pp. 636-637.
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