Further studies on adriamycin induced in vitro lipid peroxidation

T. Facchinetti, M. Müh-Zange, M. Salmona, M. Carini, H. Remmer

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Adriamycin (AM)-induced lipid peroxidation was studied in rat liver microsomal system, measuring colour produced by thiobarbituric acid (TBA) reactive material and the development of volatile hydrocarbons. The onset of this degradative process is closely related to the AM content. This phenomenon appears to be highly influenced by the buffer used for the microsomal preparation. The effect of AM on Fe-ADP-induced lipid peroxidation in liver microsomes has also been studied.

Original languageEnglish
Pages (from-to)357-367
Number of pages11
JournalChemico-Biological Interactions
Volume38
Issue number3
DOIs
Publication statusPublished - 1982

Fingerprint

Doxorubicin
Lipid Peroxidation
Lipids
Liver
Liver Microsomes
Hydrocarbons
Adenosine Diphosphate
Rats
Buffers
Color
In Vitro Techniques
thiobarbituric acid

ASJC Scopus subject areas

  • Toxicology

Cite this

Further studies on adriamycin induced in vitro lipid peroxidation. / Facchinetti, T.; Müh-Zange, M.; Salmona, M.; Carini, M.; Remmer, H.

In: Chemico-Biological Interactions, Vol. 38, No. 3, 1982, p. 357-367.

Research output: Contribution to journalArticle

Facchinetti, T. ; Müh-Zange, M. ; Salmona, M. ; Carini, M. ; Remmer, H. / Further studies on adriamycin induced in vitro lipid peroxidation. In: Chemico-Biological Interactions. 1982 ; Vol. 38, No. 3. pp. 357-367.
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