Abstract
Adriamycin (AM)-induced lipid peroxidation was studied in rat liver microsomal system, measuring colour produced by thiobarbituric acid (TBA) reactive material and the development of volatile hydrocarbons. The onset of this degradative process is closely related to the AM content. This phenomenon appears to be highly influenced by the buffer used for the microsomal preparation. The effect of AM on Fe-ADP-induced lipid peroxidation in liver microsomes has also been studied.
| Original language | English |
|---|---|
| Pages (from-to) | 357-367 |
| Number of pages | 11 |
| Journal | Chemico-Biological Interactions |
| Volume | 38 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1982 |
ASJC Scopus subject areas
- Toxicology
Fingerprint Dive into the research topics of 'Further studies on adriamycin induced in vitro lipid peroxidation'. Together they form a unique fingerprint.
Cite this
Facchinetti, T., Müh-Zange, M., Salmona, M., Carini, M., & Remmer, H. (1982). Further studies on adriamycin induced in vitro lipid peroxidation. Chemico-Biological Interactions, 38(3), 357-367. https://doi.org/10.1016/0009-2797(82)90065-5