Further studies on adriamycin induced in vitro lipid peroxidation

T. Facchinetti; M. Müh-Zange; M. Salmona; M. Carini; H. Remmer

doi:10.1016/0009-2797(82)90065-5

Further studies on adriamycin induced in vitro lipid peroxidation

T. Facchinetti, M. Müh-Zange, M. Salmona, M. Carini, H. Remmer

Istituto di Ricerche Farmacologiche "Mario Negri"

Research output: Contribution to journal › Article › peer-review

Abstract

Adriamycin (AM)-induced lipid peroxidation was studied in rat liver microsomal system, measuring colour produced by thiobarbituric acid (TBA) reactive material and the development of volatile hydrocarbons. The onset of this degradative process is closely related to the AM content. This phenomenon appears to be highly influenced by the buffer used for the microsomal preparation. The effect of AM on Fe-ADP-induced lipid peroxidation in liver microsomes has also been studied.

Original language	English
Pages (from-to)	357-367
Number of pages	11
Journal	Chemico-Biological Interactions
Volume	38
Issue number	3
DOIs	https://doi.org/10.1016/0009-2797(82)90065-5
Publication status	Published - 1982

ASJC Scopus subject areas

Toxicology

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10.1016/0009-2797(82)90065-5

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abstract = "Adriamycin (AM)-induced lipid peroxidation was studied in rat liver microsomal system, measuring colour produced by thiobarbituric acid (TBA) reactive material and the development of volatile hydrocarbons. The onset of this degradative process is closely related to the AM content. This phenomenon appears to be highly influenced by the buffer used for the microsomal preparation. The effect of AM on Fe-ADP-induced lipid peroxidation in liver microsomes has also been studied.",

author = "T. Facchinetti and M. M{\"u}h-Zange and M. Salmona and M. Carini and H. Remmer",

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AU - Facchinetti, T.

AU - Müh-Zange, M.

AU - Salmona, M.

AU - Carini, M.

AU - Remmer, H.

PY - 1982

Y1 - 1982

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Further studies on adriamycin induced in vitro lipid peroxidation

Abstract

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