Futsal and continuous exercise induce similar changes in specific skeletal muscle signalling proteins

F. R. Serpiello, M. J. McKenna, G. Coratella, J. F. Markworth, C. Tarperi, D. Bishop, N. K. Stepto, D. Cameron-Smith, F. Schena

Research output: Contribution to journalArticle

Abstract

Exercise elicits skeletal-muscle adaptations which are important for improved health outcomes. We compared the effects of a futsal game (FUT) and moderate-intensity continuous exercise (MOD), on the skeletal-muscle protein signalling responses in young, healthy individuals. 16 men undertook an incremental exercise test and a resting muscle biopsy performed >48 h apart. They were then randomly allocated to either FUT (n=12) consisting of 2 x 20 min halves, or MOD (n=8) consisting of a work-matched running bout performed at an intensity corresponding to the individual ventilatory threshold 1. Work matching was achieved by means of triaxial accelerometers. Immediately after FUT and MOD, participants underwent a second biopsy to assess exercise-induced changes in protein signalling. Total and phosphorylated protein abundance was assessed via western blotting. Both FUT and MOD altered signalling responses in skeletal muscle. FUT increased total ATF2 protein abundance (p=0.048) and phosphorylation (p=0.029), while no changes occurred with MOD. Both exercise regimes increased ACC phosphorylation (p=0.01) and returned a trend for increased p38MAPK phosphorylation. Futsal may be employed as an alternative to continuous exercise to elicit muscle adaptations which may be associated with improved health outcomes. As only FUT increased ATF2 activation, this protein might be a target of future investigation on exercise-induced signalling.

Original languageEnglish
Pages (from-to)863-870
Number of pages8
JournalInternational Journal of Sports Medicine
Volume35
Issue number10
DOIs
Publication statusPublished - Sep 1 2014

ASJC Scopus subject areas

  • Medicine(all)

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    Serpiello, F. R., McKenna, M. J., Coratella, G., Markworth, J. F., Tarperi, C., Bishop, D., Stepto, N. K., Cameron-Smith, D., & Schena, F. (2014). Futsal and continuous exercise induce similar changes in specific skeletal muscle signalling proteins. International Journal of Sports Medicine, 35(10), 863-870. https://doi.org/10.1055/s-0034-1367045