TY - JOUR
T1 - Future perspectives in melanoma research. Meeting report from the " Melanoma Bridge. Napoli, December 2nd-4th 2012"
AU - Ascierto, Paolo A.
AU - Grimaldi, Antonio M.
AU - Acquavella, Nicolas
AU - Borgognoni, Lorenzo
AU - Calabrò, Luana
AU - Cascinelli, Natale
AU - Cesano, Alessandra
AU - Del Vecchio, Michele
AU - Eggermont, Alexander M.
AU - Faries, Mark
AU - Ferrone, Soldano
AU - Fox, Bernard A.
AU - Gajewski, Thomas F.
AU - Galon, Jérôme
AU - Gnjatic, Sacha
AU - Gogas, Helen
AU - Kashani-Sabet, Mohammed
AU - Kaufman, Howard L.
AU - Larkin, James
AU - Lo, Roger S.
AU - Mantovani, Alberto
AU - Margolin, Kim
AU - Melief, Cornelis
AU - McArthur, Grant
AU - Palmieri, Giuseppe
AU - Puzanov, Igor
AU - Ribas, Antoni
AU - Seliger, Barbara
AU - Sosman, Jeff
AU - Suenaert, Peter
AU - Tarhini, Ahmad A.
AU - Trinchieri, Giorgio
AU - Vidal-Vanaclocha, Fernando
AU - Wang, Ena
AU - Ciliberto, Gennaro
AU - Mozzillo, Nicola
AU - Marincola, Francesco M.
AU - Thurin, Magdalena
PY - 2013/6/3
Y1 - 2013/6/3
N2 - Recent insights into the genetic and somatic aberrations have initiated a new era of rapidly evolving targeted and immune-based treatments for melanoma. After decades of unsuccessful attempts to finding a more effective cure in the treatment of melanoma now we have several drugs active in melanoma. The possibility to use these drugs in combination to improve responses to overcome the resistance, to potentiate the action of immune system with the new immunomodulating antibodies, and identification of biomarkers that can predict the response to a particular therapy represent new concepts and approaches in the clinical management of melanoma. The third " Melanoma Research: " A bridge from Naples to the World" meeting, shortened as " Bridge Melanoma Meeting" took place in Naples, December 2 to 4th, 2012. The four topics of discussion at this meeting were: advances in molecular profiling and novel biomarkers, combination therapies, novel concepts toward integrating biomarkers and therapies into contemporary clinical management of patients with melanoma across the entire spectrum of disease stage, and the knowledge gained from the biology of tumor microenvironment across different tumors as a bridge to impact on prognosis and response to therapy in melanoma. This international congress gathered more than 30 international faculty members who in an interactive atmosphere which stimulated discussion and exchange of their experience regarding the most recent advances in research and clinical management of melanoma patients.
AB - Recent insights into the genetic and somatic aberrations have initiated a new era of rapidly evolving targeted and immune-based treatments for melanoma. After decades of unsuccessful attempts to finding a more effective cure in the treatment of melanoma now we have several drugs active in melanoma. The possibility to use these drugs in combination to improve responses to overcome the resistance, to potentiate the action of immune system with the new immunomodulating antibodies, and identification of biomarkers that can predict the response to a particular therapy represent new concepts and approaches in the clinical management of melanoma. The third " Melanoma Research: " A bridge from Naples to the World" meeting, shortened as " Bridge Melanoma Meeting" took place in Naples, December 2 to 4th, 2012. The four topics of discussion at this meeting were: advances in molecular profiling and novel biomarkers, combination therapies, novel concepts toward integrating biomarkers and therapies into contemporary clinical management of patients with melanoma across the entire spectrum of disease stage, and the knowledge gained from the biology of tumor microenvironment across different tumors as a bridge to impact on prognosis and response to therapy in melanoma. This international congress gathered more than 30 international faculty members who in an interactive atmosphere which stimulated discussion and exchange of their experience regarding the most recent advances in research and clinical management of melanoma patients.
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U2 - 10.1186/1479-5876-11-137
DO - 10.1186/1479-5876-11-137
M3 - Article
C2 - 23731854
AN - SCOPUS:84878374050
VL - 11
JO - Journal of Translational Medicine
JF - Journal of Translational Medicine
SN - 1479-5876
IS - 1
M1 - 137
ER -