TY - JOUR
T1 - Future Research Directions in Sleep and ADHD
T2 - Report of a Consensus Working Group
AU - Owens, Judith
AU - Gruber, Reut
AU - Brown, Thomas
AU - Corkum, Penny
AU - Cortese, Samuele
AU - O'Brien, Louise
AU - Stein, Mark
AU - Weiss, Margaret
PY - 2013/10
Y1 - 2013/10
N2 - Objective: To explore relationships between basic and translational science research regarding sleep and ADHD in children. Method: A multidisciplinary group of experts in pediatric sleep medicine and ADHD convened in November 2010 to summarize the current literature, delineate knowledge gaps, and formulate recommendations regarding future research directions and priorities. Results: Six major research areas of interest were identified: (a) brain centers regulating sleep, arousal, and attention; (b) neurotransmitter systems involved in both sleep and attention regulation; (c) alterations of neural systems regulating sleep in ADHD; (d) phenotypic similarities between behavioral, mood, and cognitive manifestations of insufficient/disrupted sleep and ADHD; (e) hypoarousal and sleepiness in ADHD; and (f) external sleep-wake signals that affect sleep regulation in ADHD. Conclusion: An enhanced understanding of the complex mechanisms regulating sleep promotion, wakefulness, and attention may contribute to new insights regarding the core impairments in ADHD and lead to the development of new therapies.
AB - Objective: To explore relationships between basic and translational science research regarding sleep and ADHD in children. Method: A multidisciplinary group of experts in pediatric sleep medicine and ADHD convened in November 2010 to summarize the current literature, delineate knowledge gaps, and formulate recommendations regarding future research directions and priorities. Results: Six major research areas of interest were identified: (a) brain centers regulating sleep, arousal, and attention; (b) neurotransmitter systems involved in both sleep and attention regulation; (c) alterations of neural systems regulating sleep in ADHD; (d) phenotypic similarities between behavioral, mood, and cognitive manifestations of insufficient/disrupted sleep and ADHD; (e) hypoarousal and sleepiness in ADHD; and (f) external sleep-wake signals that affect sleep regulation in ADHD. Conclusion: An enhanced understanding of the complex mechanisms regulating sleep promotion, wakefulness, and attention may contribute to new insights regarding the core impairments in ADHD and lead to the development of new therapies.
KW - ADHD
KW - circadian rhythms
KW - sleep
UR - http://www.scopus.com/inward/record.url?scp=84883786491&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84883786491&partnerID=8YFLogxK
U2 - 10.1177/1087054712457992
DO - 10.1177/1087054712457992
M3 - Article
C2 - 22982880
AN - SCOPUS:84883786491
VL - 17
SP - 550
EP - 564
JO - Journal of Attention Disorders
JF - Journal of Attention Disorders
SN - 1087-0547
IS - 7
ER -