GabaB agonists for the treatment of alcohol use disorder

Antonio Mirijello, Fabio Caputo, Gabriele Vassallo, Benjamin Rolland, Claudia Tarli, Antonio Gasbarrini, Giovanni Addolorato

Research output: Contribution to journalArticle

Abstract

Almost 10% of the world’s population is affected by alcohol use disorder (AUD). The combination between psychosocial intervention and pharmacological treatment seems to be the most effective approach for patients affected by AUD. Among effective drugs useful in the treatment of AUD, GABAB-ergic medications have been tested with encouraging results (i.e. sodium oxybate, baclofen, gabapentin, pregabalin and tiagabine). The present review will summarize available data on these medications.

Original languageEnglish
Pages (from-to)3367-3372
Number of pages6
JournalCurrent Pharmaceutical Design
Volume21
Issue number23
Publication statusPublished - Jul 1 2015

Fingerprint

Alcohols
Sodium Oxybate
Baclofen
Therapeutics
Pharmacology
Pharmaceutical Preparations
Population
gabapentin
Pregabalin
tiagabine

Keywords

  • Alcohol use disorder
  • Craving
  • GABA<inf>B</inf> agonists
  • Pharmacological treatment

ASJC Scopus subject areas

  • Drug Discovery
  • Pharmacology

Cite this

Mirijello, A., Caputo, F., Vassallo, G., Rolland, B., Tarli, C., Gasbarrini, A., & Addolorato, G. (2015). GabaB agonists for the treatment of alcohol use disorder. Current Pharmaceutical Design, 21(23), 3367-3372.

GabaB agonists for the treatment of alcohol use disorder. / Mirijello, Antonio; Caputo, Fabio; Vassallo, Gabriele; Rolland, Benjamin; Tarli, Claudia; Gasbarrini, Antonio; Addolorato, Giovanni.

In: Current Pharmaceutical Design, Vol. 21, No. 23, 01.07.2015, p. 3367-3372.

Research output: Contribution to journalArticle

Mirijello, A, Caputo, F, Vassallo, G, Rolland, B, Tarli, C, Gasbarrini, A & Addolorato, G 2015, 'GabaB agonists for the treatment of alcohol use disorder', Current Pharmaceutical Design, vol. 21, no. 23, pp. 3367-3372.
Mirijello A, Caputo F, Vassallo G, Rolland B, Tarli C, Gasbarrini A et al. GabaB agonists for the treatment of alcohol use disorder. Current Pharmaceutical Design. 2015 Jul 1;21(23):3367-3372.
Mirijello, Antonio ; Caputo, Fabio ; Vassallo, Gabriele ; Rolland, Benjamin ; Tarli, Claudia ; Gasbarrini, Antonio ; Addolorato, Giovanni. / GabaB agonists for the treatment of alcohol use disorder. In: Current Pharmaceutical Design. 2015 ; Vol. 21, No. 23. pp. 3367-3372.
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