GabaB agonists for the treatment of alcohol use disorder

Antonio Mirijello, Fabio Caputo, Gabriele Vassallo, Benjamin Rolland, Claudia Tarli, Antonio Gasbarrini, Giovanni Addolorato

Research output: Contribution to journalArticlepeer-review


Almost 10% of the world’s population is affected by alcohol use disorder (AUD). The combination between psychosocial intervention and pharmacological treatment seems to be the most effective approach for patients affected by AUD. Among effective drugs useful in the treatment of AUD, GABAB-ergic medications have been tested with encouraging results (i.e. sodium oxybate, baclofen, gabapentin, pregabalin and tiagabine). The present review will summarize available data on these medications.

Original languageEnglish
Pages (from-to)3367-3372
Number of pages6
JournalCurrent Pharmaceutical Design
Issue number23
Publication statusPublished - Jul 1 2015


  • Alcohol use disorder
  • Craving
  • GABA<inf>B</inf> agonists
  • Pharmacological treatment

ASJC Scopus subject areas

  • Drug Discovery
  • Pharmacology


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