Abstract
The aim of this study was to determine the effect of Billroth II gastric resection (BII) without vagotomy on gallbladder contraction in response to meal and CCK-OP infusion. Fourteen duodenal ulcer patients were studied before surgery and six months postoperatively. Gallbladder Volume was measured by real-time ultrasonography. After surgery, there was a significant increase in fasting gallbladder volume (P <0.05). Postprandial gallbladder emptying was not significantly affected by gastrectomy apart from a trend towards a shorter t 1/2 and a larger ejection volume. In addition, postoperative gallbladder relaxation was more pronounced at time 120 min. In response to cholecystokinin-octapeptida (CCK-OP) infusion, there was a significant decrease of t 1/2 after BII and a prolonged contraction with a significantly reduced gallbladder volume. Our data show that the gallbladder response both to meal and CCK-OP infusion is modified after BII and a larger postoperative gallbladder volume may play a role in the pathogenesis of gallstone disease after gastric surgery.
| Original language | English |
|---|---|
| Pages (from-to) | 145-149 |
| Number of pages | 5 |
| Journal | Neurogastroenterology and Motility |
| Volume | 7 |
| Issue number | 3 |
| Publication status | Published - 1995 |
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Keywords
- Billroth II gastric resection
- Gallbladder motility
- Real-time ultrasonography
ASJC Scopus subject areas
- Physiology
- Gastroenterology
- Neuroscience(all)
Cite this
Gallbladder motility before and after Billroth II gastric resection. / Chiloiro, M.; Pezzolla, F.; Riezzo, G.; Maselli, M. A.; Lorusso, D.
In: Neurogastroenterology and Motility, Vol. 7, No. 3, 1995, p. 145-149.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Gallbladder motility before and after Billroth II gastric resection
AU - Chiloiro, M.
AU - Pezzolla, F.
AU - Riezzo, G.
AU - Maselli, M. A.
AU - Lorusso, D.
PY - 1995
Y1 - 1995
N2 - The aim of this study was to determine the effect of Billroth II gastric resection (BII) without vagotomy on gallbladder contraction in response to meal and CCK-OP infusion. Fourteen duodenal ulcer patients were studied before surgery and six months postoperatively. Gallbladder Volume was measured by real-time ultrasonography. After surgery, there was a significant increase in fasting gallbladder volume (P <0.05). Postprandial gallbladder emptying was not significantly affected by gastrectomy apart from a trend towards a shorter t 1/2 and a larger ejection volume. In addition, postoperative gallbladder relaxation was more pronounced at time 120 min. In response to cholecystokinin-octapeptida (CCK-OP) infusion, there was a significant decrease of t 1/2 after BII and a prolonged contraction with a significantly reduced gallbladder volume. Our data show that the gallbladder response both to meal and CCK-OP infusion is modified after BII and a larger postoperative gallbladder volume may play a role in the pathogenesis of gallstone disease after gastric surgery.
AB - The aim of this study was to determine the effect of Billroth II gastric resection (BII) without vagotomy on gallbladder contraction in response to meal and CCK-OP infusion. Fourteen duodenal ulcer patients were studied before surgery and six months postoperatively. Gallbladder Volume was measured by real-time ultrasonography. After surgery, there was a significant increase in fasting gallbladder volume (P <0.05). Postprandial gallbladder emptying was not significantly affected by gastrectomy apart from a trend towards a shorter t 1/2 and a larger ejection volume. In addition, postoperative gallbladder relaxation was more pronounced at time 120 min. In response to cholecystokinin-octapeptida (CCK-OP) infusion, there was a significant decrease of t 1/2 after BII and a prolonged contraction with a significantly reduced gallbladder volume. Our data show that the gallbladder response both to meal and CCK-OP infusion is modified after BII and a larger postoperative gallbladder volume may play a role in the pathogenesis of gallstone disease after gastric surgery.
KW - Billroth II gastric resection
KW - Gallbladder motility
KW - Real-time ultrasonography
UR - http://www.scopus.com/inward/record.url?scp=0029087656&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029087656&partnerID=8YFLogxK
M3 - Article
C2 - 8536158
AN - SCOPUS:0029087656
VL - 7
SP - 145
EP - 149
JO - Neurogastroenterology and Motility
JF - Neurogastroenterology and Motility
SN - 1350-1925
IS - 3
ER -