Gallbladder motility before and after Billroth II gastric resection

M. Chiloiro, F. Pezzolla, G. Riezzo, M. A. Maselli, D. Lorusso

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of this study was to determine the effect of Billroth II gastric resection (BII) without vagotomy on gallbladder contraction in response to meal and CCK-OP infusion. Fourteen duodenal ulcer patients were studied before surgery and six months postoperatively. Gallbladder Volume was measured by real-time ultrasonography. After surgery, there was a significant increase in fasting gallbladder volume (P <0.05). Postprandial gallbladder emptying was not significantly affected by gastrectomy apart from a trend towards a shorter t 1/2 and a larger ejection volume. In addition, postoperative gallbladder relaxation was more pronounced at time 120 min. In response to cholecystokinin-octapeptida (CCK-OP) infusion, there was a significant decrease of t 1/2 after BII and a prolonged contraction with a significantly reduced gallbladder volume. Our data show that the gallbladder response both to meal and CCK-OP infusion is modified after BII and a larger postoperative gallbladder volume may play a role in the pathogenesis of gallstone disease after gastric surgery.

Original languageEnglish
Pages (from-to)145-149
Number of pages5
JournalNeurogastroenterology and Motility
Volume7
Issue number3
Publication statusPublished - 1995

Keywords

  • Billroth II gastric resection
  • Gallbladder motility
  • Real-time ultrasonography

ASJC Scopus subject areas

  • Physiology
  • Gastroenterology
  • Neuroscience(all)

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