Gallstones and uterine fibroids

G. Misciagna, V. Mangini, C. Messa, V. Argese, M. Lacatena, R. Trentadue, I. Giorgio

Research output: Contribution to journalArticlepeer-review


In a series published in 1961, an unusual frequency of hysterectomies for uterine leiomyomas (fibroids) was reported in women with gallstone. The purpose of this study was to confirm the association between gallstones and uterine leiomyomas with a patient control study and to investigate its physiopathologic basis comparing the cholesterol saturation of bile in women with gallstones, in women with leiomyomas but no gallstones and in those in the control group with no gallstones or leiomyomas. Patients admitted to the surgical department have, routinely, echography of the gallbladder before and manual exploration of the pelvic floor during surgical intervention. For the first part of the study, we collected information concerning the diagnosis of leiomyomas from the operating room registers and about the diagnosis of gallstones from the clinical records. In 1982, 42 of 139 women operated upon consecutively for gallstones and five of 69 operated upon for other diseases of the gastrointestinal tract had leiomyomas, a statistically significant difference (chi-square test, p

Original languageEnglish
Pages (from-to)429-434
Number of pages6
JournalSurgery Gynecology and Obstetrics
Issue number5
Publication statusPublished - 1987

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Surgery


Dive into the research topics of 'Gallstones and uterine fibroids'. Together they form a unique fingerprint.

Cite this