Ganciclovir penetrates into the cerebrospinal fluid of an infant with congenital cytomegalovirus infection Neonatology and Fetal Medicine

Fabio Natale, Bianca Bizzarri, Veronica Cardi, Aurelia Gaeta, Paola Villani, Giuseppina Liuzzi, Mario De Curtis

Research output: Contribution to journalArticle

Abstract

Currently, there is no evidence whether ganciclovir, or its oral prodrug valganciclovir, penetrates into the cerebrospinal fluid of human infants treated for congenital cytomegalovirus infection. Here, we report a case study providing evidence that ganciclovir, administered as valganciclovir, reaches the infant's cerebrospinal fluid when used at the currently recommended dose for congenital cytomegalovirus infection.

Original languageEnglish
Article number41
JournalItalian Journal of Pediatrics
Volume41
Issue number1
DOIs
Publication statusPublished - Mar 31 2015

Keywords

  • Cerebrospinal fluid
  • Congenital infection
  • Cytomegalovirus
  • Ganciclovir
  • Valganciclovir

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Fingerprint Dive into the research topics of 'Ganciclovir penetrates into the cerebrospinal fluid of an infant with congenital cytomegalovirus infection Neonatology and Fetal Medicine'. Together they form a unique fingerprint.

  • Cite this