Abstract
An 8-year-old male castrated cat was referred for sudden onset of lameness. Physical examination revealed a 1 × 2 × 1 cm mass originating from a footpad of the right hind leg. A diagnosis of ganglioneuroblastoma was suggested by the tumour appearance following histopathological staining with haematoxylin and eosin and haematoxylin/van Gieson. Immunohistochemical staining for glial fibrillary acidic protein (GFAP), vimentin, neuron-specific enolase (NSE), neurofilament and S100 further confirmed the diagnosis. The staging process did not indicate metastatic spread. The cat was treated with three sessions of electrochemotherapy (ECT) 1 week apart, following local injection of bleomycin. The tumour had completely regressed within 1 week of the third ECT application and remained in remission for 402 days at which time a small recurrence was noted. The animal was given a further session of ECT using intra-lesional cisplatin and again went into remission. It remained tumour free at 450 days. Electrochemotherapy is considered a safe and effective treatment for localised neoplasms of cats and dogs and warrants further investigation.
Original language | English |
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Pages (from-to) | 291-293 |
Number of pages | 3 |
Journal | Veterinary Journal |
Volume | 178 |
Issue number | 2 |
DOIs | |
Publication status | Published - Nov 2008 |
Keywords
- Biphasic pulse
- Bleomycin
- Cisplatin
- Electrochemotherapy
ASJC Scopus subject areas
- Animal Science and Zoology
- veterinary(all)