Abstract
The complete definition of the chemical structure of GD1b-ganglioside (GD1b) lactone isolated from human brain has been given by means of spectrometric and spectroscopic analyses. GD1h lactone contains a single ester linkage involving the external sialic acid carboxyl group and the C-9 hydroxyl group of the internal sialic acid unit. A synthetic lactone of GD1b prepared treating GD1b with glacial acetic acid characterized in the same way showed an identical chemical structure.
Original language | English |
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Pages (from-to) | 119-127 |
Number of pages | 9 |
Journal | Glycoconjugate Journal |
Volume | 4 |
Issue number | 2 |
DOIs | |
Publication status | Published - Jun 1987 |
Keywords
- ganglioside lactones
- NMR
ASJC Scopus subject areas
- Biochemistry