Ganglioside pattern of normal human brain, from samples obtained at surgery. A study especially referred to alkali labile species

L. Riboni, A. Malesci, S. M. Gaini, S. Sonnino, R. Ghidoni, G. Tettamanti

Research output: Contribution to journalArticlepeer-review

Abstract

The ganglioside pattern from normal human temporal cortex and cerebellum has been studied in fresh specimens obtained at surgery. The analyses have been performed by two-dimensional thin layer chromatography with an intermediate ammonia treatment which is a methodology particularly suitable for resolving alkali labile gangliosides. Alkali labile gangliosides were detected in all the analyzed specimens and their content contributed to 23% and 11% of total lipid bound sialic acid, in temporal cortex and cerebellum, respectively.

Original languageEnglish
Pages (from-to)1943-1946
Number of pages4
JournalJournal of Biochemistry
Volume96
Issue number6
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Biochemistry
  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Radiology Nuclear Medicine and imaging
  • Molecular Biology

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