Gas chromatographic determination of acenocoumarin in human plasma

G. Bianchetti, R. Latini, P. L. Morselli

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A method based on solvent extraction, formation of a fluorinated derivative and quantitation by gas-liquid chromatography with electron-capture detection has been developed for the determination of acenocoumarin in plasma. The specificity and sensitivity of the procedure appear to be satisfactory for drug level measurements in human plasma. Its relative simplicity permits its use in routine analysis.

Original languageEnglish
Pages (from-to)331-335
Number of pages5
JournalJournal of Chromatography A
Volume124
Issue number2
DOIs
Publication statusPublished - Sep 15 1976

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Acenocoumarol
Plasma (human)
Level measurement
Liquid chromatography
Solvent extraction
Gas chromatography
Gases
Derivatives
Plasmas
Electrons
Pharmaceutical Preparations
Gas Chromatography
Sensitivity and Specificity

ASJC Scopus subject areas

  • Analytical Chemistry
  • Clinical Biochemistry
  • Molecular Medicine

Cite this

Gas chromatographic determination of acenocoumarin in human plasma. / Bianchetti, G.; Latini, R.; Morselli, P. L.

In: Journal of Chromatography A, Vol. 124, No. 2, 15.09.1976, p. 331-335.

Research output: Contribution to journalArticle

Bianchetti, G. ; Latini, R. ; Morselli, P. L. / Gas chromatographic determination of acenocoumarin in human plasma. In: Journal of Chromatography A. 1976 ; Vol. 124, No. 2. pp. 331-335.
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