Abstract
A method based on solvent extraction, formation of a fluorinated derivative and quantitation by gas-liquid chromatography with electron-capture detection has been developed for the determination of acenocoumarin in plasma. The specificity and sensitivity of the procedure appear to be satisfactory for drug level measurements in human plasma. Its relative simplicity permits its use in routine analysis.
| Original language | English |
|---|---|
| Pages (from-to) | 331-335 |
| Number of pages | 5 |
| Journal | Journal of Chromatography A |
| Volume | 124 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Sep 15 1976 |
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ASJC Scopus subject areas
- Analytical Chemistry
- Clinical Biochemistry
- Molecular Medicine
Cite this
Gas chromatographic determination of acenocoumarin in human plasma. / Bianchetti, G.; Latini, R.; Morselli, P. L.
In: Journal of Chromatography A, Vol. 124, No. 2, 15.09.1976, p. 331-335.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Gas chromatographic determination of acenocoumarin in human plasma
AU - Bianchetti, G.
AU - Latini, R.
AU - Morselli, P. L.
PY - 1976/9/15
Y1 - 1976/9/15
N2 - A method based on solvent extraction, formation of a fluorinated derivative and quantitation by gas-liquid chromatography with electron-capture detection has been developed for the determination of acenocoumarin in plasma. The specificity and sensitivity of the procedure appear to be satisfactory for drug level measurements in human plasma. Its relative simplicity permits its use in routine analysis.
AB - A method based on solvent extraction, formation of a fluorinated derivative and quantitation by gas-liquid chromatography with electron-capture detection has been developed for the determination of acenocoumarin in plasma. The specificity and sensitivity of the procedure appear to be satisfactory for drug level measurements in human plasma. Its relative simplicity permits its use in routine analysis.
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UR - http://www.scopus.com/inward/citedby.url?scp=0017169805&partnerID=8YFLogxK
U2 - 10.1016/S0021-9673(00)89748-4
DO - 10.1016/S0021-9673(00)89748-4
M3 - Article
C2 - 965466
AN - SCOPUS:0017169805
VL - 124
SP - 331
EP - 335
JO - Journal of Chromatography A
JF - Journal of Chromatography A
SN - 0021-9673
IS - 2
ER -