Gastric electrical activity in normal neonates during the first year of life: Effect of feeding with breast milk and formula

Giuseppe Riezzo, Rosa Maria Castellana, Teresa De Bellis, Francesca Laforgia, Flavia Indrio, Marisa Chiloiro

Research output: Contribution to journalArticle

Abstract

Background. To evaluate the effect of feeding with milk on the gastrointestinal tract, we studied gastric electrical activity in 27 healthy fullterm newborns (15 formula-fed newborns and 12 breast-fed newborns) during the first 6 months of life. Methods. Three-hour electrogastrography (EGG) recordings were performed, using portable equipment, from the third to fifth day after birth until 6 months, at 3-month intervals. The EGG parameters were calculated as raw and integrated data, the latter as AUC of the whole postprandial period. Results. There was a significant difference in the fasting 3-cpm activity between the two groups (repeated measures analysis of variance [ANOVA] P = 0.02; multiple comparisons: formula milk at birth vs breast milk at birth P <0.001). In addition, a significant change in the percentage of postprandial bradygastria was found at 6 months, 1 month after weaning (repeated measures ANOVA, P = 0.01; multiple comparisons: formula milk at 6 months vs formula milk at 3 months, P = 0.03, formula milk at 6 months vs formula milk at birth, P = 0.02; breast milk at 6 months vs breast milk at 3 months, P = 0.03, breast milk at 6 months vs breast milk at birth P = 0.02). Conclusions. An adult-like gastric 3-cpm activity can be observed in breast-fed newborns in contrast to formula-fed ones, probably as an effect of colostrum. The high bradygastria percentage recorded at 6 months of life might be the result of an increased low-frequency component of the EGG signal because of the transition to a mixed diet.

Original languageEnglish
Pages (from-to)836-843
Number of pages8
JournalJournal of Gastroenterology
Volume38
Issue number9
DOIs
Publication statusPublished - Sep 2003

Keywords

  • Breast milk
  • Electrogastrography
  • Enteral feeding
  • Formula milk
  • Gastrointestinal motility
  • Ontogeny

ASJC Scopus subject areas

  • Gastroenterology

Fingerprint Dive into the research topics of 'Gastric electrical activity in normal neonates during the first year of life: Effect of feeding with breast milk and formula'. Together they form a unique fingerprint.

  • Cite this