Gastric gastrinoma and diffuse g cell hyperplasia associated with chronic atrophic gastritis: Endoscopic detection and removal

A. Russo; R. Buffa; G. Grasso; G. Giannone; G. Sanfilippo; F. Sessa; E. Solcia

doi:10.1159/000198484

Gastric gastrinoma and diffuse g cell hyperplasia associated with chronic atrophic gastritis: Endoscopic detection and removal

A. Russo, R. Buffa, G. Grasso, G. Giannone, G. Sanfilippo, F. Sessa, E. Solcia

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

Chronic atrophic gastritis and a sessile polyp were diagnosed during gastroscopy of a patient with splenomegaly and portal hypertension. The polyp was removed endoscopically. Histologically, it proved to be an endocrine tumour, which was identified as gastrinoma by immunohistochemistry. Then, hypergastrinemia was four.d and gastrectomy was performed to ensure complete removal of the tumour. The surgical specimen showed G cell hyperplasia of the antro-pyloric mucosa and severe atrophic gastritis with scattered argyrophil micronodules in the corpus-fundus region. 3 years after this treatment the patient is well.

Original language	English
Pages (from-to)	416-419
Number of pages	4
Journal	Digestion
Volume	20
Issue number	6
DOIs	https://doi.org/10.1159/000198484
Publication status	Published - 1980

Keywords

Atrophic gastritits
Endoscopy
Gastric
Gastrinoma
Histochemistry
Histopathology

ASJC Scopus subject areas

Gastroenterology

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10.1159/000198484

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title = "Gastric gastrinoma and diffuse g cell hyperplasia associated with chronic atrophic gastritis: Endoscopic detection and removal",

abstract = "Chronic atrophic gastritis and a sessile polyp were diagnosed during gastroscopy of a patient with splenomegaly and portal hypertension. The polyp was removed endoscopically. Histologically, it proved to be an endocrine tumour, which was identified as gastrinoma by immunohistochemistry. Then, hypergastrinemia was four.d and gastrectomy was performed to ensure complete removal of the tumour. The surgical specimen showed G cell hyperplasia of the antro-pyloric mucosa and severe atrophic gastritis with scattered argyrophil micronodules in the corpus-fundus region. 3 years after this treatment the patient is well.",

keywords = "Atrophic gastritits, Endoscopy, Gastric, Gastrinoma, Histochemistry, Histopathology",

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year = "1980",

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T1 - Gastric gastrinoma and diffuse g cell hyperplasia associated with chronic atrophic gastritis

T2 - Endoscopic detection and removal

AU - Russo, A.

AU - Buffa, R.

AU - Grasso, G.

AU - Giannone, G.

AU - Sanfilippo, G.

AU - Sessa, F.

AU - Solcia, E.

PY - 1980

Y1 - 1980

N2 - Chronic atrophic gastritis and a sessile polyp were diagnosed during gastroscopy of a patient with splenomegaly and portal hypertension. The polyp was removed endoscopically. Histologically, it proved to be an endocrine tumour, which was identified as gastrinoma by immunohistochemistry. Then, hypergastrinemia was four.d and gastrectomy was performed to ensure complete removal of the tumour. The surgical specimen showed G cell hyperplasia of the antro-pyloric mucosa and severe atrophic gastritis with scattered argyrophil micronodules in the corpus-fundus region. 3 years after this treatment the patient is well.

AB - Chronic atrophic gastritis and a sessile polyp were diagnosed during gastroscopy of a patient with splenomegaly and portal hypertension. The polyp was removed endoscopically. Histologically, it proved to be an endocrine tumour, which was identified as gastrinoma by immunohistochemistry. Then, hypergastrinemia was four.d and gastrectomy was performed to ensure complete removal of the tumour. The surgical specimen showed G cell hyperplasia of the antro-pyloric mucosa and severe atrophic gastritis with scattered argyrophil micronodules in the corpus-fundus region. 3 years after this treatment the patient is well.

KW - Atrophic gastritits

KW - Endoscopy

KW - Gastric

KW - Gastrinoma

KW - Histochemistry

KW - Histopathology

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Gastric gastrinoma and diffuse g cell hyperplasia associated with chronic atrophic gastritis: Endoscopic detection and removal

Abstract

Keywords

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